Results 91 to 100 of about 1,814,913 (312)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Solvability and construction of solutions of integral equations

Вестник КазНУ. Серия математика, механика, информатика, 2017
A class of integral equations with respect to one variable function as well as to multivariable function that are solvable for any right hand side of an equation has been singled out. A necessary and sufficient condition for existence of a solution has
С. А. Айсагалиев, С. С. Айсагалиева, А. А. Кабидолданова   +2 more
doaj  

The General Solution to a System of Tensor Equations over the Split Quaternion Algebra with Applications

Mathematics
This paper presents a systematic investigation into the solvability and the general solution of a tensor equation system within the split quaternion algebra framework. As an extension of classical quaternions with distinctive pseudo-Euclidean properties,
Zong-Ru Jia, Qing-Wen Wang
doaj   +1 more source

Is There a Statistical Solution to the Generality Problem?

Erkenntnis, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dutant Julien, Olsson Erik
openaire   +5 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

On flow in weakly precessing cylinders: the general asymptotic solution

, 2012
We investigate, through both asymptotic and numerical analysis, precessionally driven flow of a homogeneous fluid confined in a fluid-filled circular cylinder that rotates rapidly about its symmetry axis and precesses slowly about a different axis that ...
Liao, Xinhao, Zhang, Keke
core  

Carbohydrate based resins for polymer assisted solution phase synthesis [PDF]

, 2003
Carbohydrate based beads can be derivatised to produce high loading resins which are comparable in both solvent compatibility and loading of required functionality to commercial polystyrene based resins, that are used in polymer assisted solution phase ...
Stonehouse, D. F.
core  

An Investigation on Mathematical Modeling of Operators on The Hilbert Domain subjected to The Equality Theory

Journal of Applied Science and Engineering
This work begins by presenting the essential and enough circumstances for the presence of the Hermitian solution to equations ΨXΦ + Φ∗YΨ∗ = Ω = Ψ∗XΦ∗+ ΦYΨ in the case where the operators are linear and bounded in a Hilbert space and in terms of the Moore-
Salim Dawood Mohsen, Ihsan Abdulsattar Awadh   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source