Results 111 to 120 of about 15,159,360 (304)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Mon. Not. R. Astron. Soc. 000, 1-28 (0000) Printed 11 February 2003 (MN L A T E X style
, 2007 The Jeans equations relate the second-order velocity moments to the density and potential of a stellar system. For general three-dimensional stellar systems, there are three equations and six independent moments.
P. T. De Zeeuw, Le General Solution
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
General solution of overdamped Josephson junction equation in the case of phase-lock
Electronic Journal of Differential Equations, 2007 The first order nonlinear ordinary differential equation $dot varphi(t) + sinvarphi(t)=B+Acosomega t$, which is commonly used as a simple model of an overdamped Josephson junction in superconductors is investigated.
Sergey I. Tertychniy
doaj
, 2019 1 online resource (12 pages)Pursuant to Public act no. 18-125, section 5; "Monday, March 25, 2019.
Connecticut. General Assembly. General Law Committee. Student Data Privacy Task Force, author
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‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
, 1893 Copia digital. España : Ministerio de Cultura y Deporte.
Sociedad General de Alumbrado de Mahón
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FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
A Survey on Solving the Matrix Equation AXB = C with Applications
MathematicsThis survey provides a comprehensive overview of the solutions to the matrix equation AXB=C over real numbers, complex numbers, quaternions, dual quaternions, dual split quaternions, and dual generalized commutative quaternions, including various special
Qing-Wen Wang, Lv-Ming Xie, Zi-Han Gao
doaj +1 more source