Results 51 to 60 of about 1,814,913 (312)

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Geodesics in the generalized Schwarzschild solution [PDF]

American Journal of Physics, 2004
Since Schwarzshild discovered the point-mass solution to Einstein’s equations that bears his name, many equivalent forms of the metric have been obtained. Using an elementary coordinate transformation, we derive the most general form for the stationary, spherically symmetric vacuum metric, which contains one free function.
Francis, Matthew R., Kosowsky, Arthur
openaire   +2 more sources

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Formation Thermodynamics of Carbamazepine with Benzamide, Para-Hydroxybenzamide and Isonicotinamide Cocrystals: Experimental and Theoretical Study

Pharmaceutics, 2022
Formation thermodynamic parameters for three cocrystals of carbamazepine (CBZ) with structurally related coformers (benzamide (BZA), para-hydroxybenzamide (4-OH-BZA) and isonicotinamide (INAM)) were determined by experimental (cocrystal solubility and ...
Alex N. Manin, Denis E. Boycov, Olga R. Simonova, Tatyana V. Volkova, Andrei V. Churakov, German L. Perlovich   +5 more
doaj   +1 more source

General Automatic Solution Generation for Social Problems

Machine Intelligence Research
Given the escalating intricacy and multifaceted nature of contemporary social systems, manually generating solutions to address pertinent social issues has become a formidable task. In response to this challenge, the rapid development of artificial intelligence has spurred the exploration of computational methodologies aimed at automatically generating
Tong Niu, Haoyu Huang, Yu Du 0010, Weihao Zhang, Luping Shi, Rong Zhao   +5 more
openaire   +2 more sources

Generalized Rationing Problems and Solutions [PDF]

SSRN Electronic Journal, 2015
An extension of the standard rationing model is introduced. Agents are not only identified by their respective claims on some amount of a scarce resource, but also by some exogenous ex-ante conditions (initial stock of resource or net worth of agents, for instance), different from claims.
Timoner Lledó, Pere, Izquierdo Aznar, Josep Maria   +1 more
openaire   +3 more sources

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro, Freda Qi, Karen Colwill, Alina D. Dorogy, Ying Liu, Michelle Science, Anne‐Claude Gingras, James M. Rini, Sumit Gupta, Sarah Alexander, Shelly Bolotin, Tania H. Watts   +11 more
wiley   +1 more source

General solution to a higher-order linear difference equation and existence of bounded solutions

Advances in Difference Equations, 2017
We present a closed-form formula for the general solution to the difference equation x n + k − q n x n = f n , n ∈ N 0 , $$x_{n+k}-q_{n}x_{n}=f_{n},\quad n\in \mathbb {N}_{0}, $$ where k ∈ N $k\in \mathbb {N}$ , ( q n ) n ∈ N 0 $(q_{n})_{n\in \mathbb {N ...
Stevo Stević
doaj   +1 more source

A Combined Experimental and Theoretical Study of Nitrofuran Antibiotics: Crystal Structures, DFT Computations, Sublimation and Solution Thermodynamics

Molecules, 2021
Single crystal of furazolidone (FZL) has been successfully obtained, and its crystal structure has been determined. Common and distinctive features of furazolidone and nitrofurantoin (NFT) crystal packing have been discussed.
Alex N. Manin, Ksenia V. Drozd, Alexander P. Voronin, Andrei V. Churakov, German L. Perlovich   +4 more
doaj   +1 more source