Results 31 to 40 of about 2,358,271 (346)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Day surgery and general anaesthesia : what makes patients anxious? [PDF]

open access: yes, 2010
For many patients the prospective of undergoing surgery and general anaesthesia is highly anxiety provoking. With the global rise in day surgery and limited nurse/ patient contact, anxiety has become a prominent issue.
Mitchell, MJ
core   +1 more source

News in Brief [PDF]

open access: yes, 2017
Alec Beekley, MD, FACS (Division of Acute Care Surgery), and John Entwistle, MD, FACS (Division of Cardiothoracic Surgery), have each been promoted to Professor of Surgery.

core   +2 more sources

General surgery admissions, operations, and patient outcomes during the COVID-19 pandemic

open access: yesArchives of Trauma Research, 2022
Background and Objectives: During the COVID-19 pandemic, hospitals were overwhelmed and non-COVID admissions were restricted due to national guidelines and decreased references.
Esmail Abdorrahim-Kashi   +6 more
doaj   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

William Arbuthnot Lane (1856-1943): Surgical Innovator and His Theory of Autointoxication. [PDF]

open access: yes, 2017
William Arbuthnot Lane contributed to the advancement of many fields of orthopedics, otolaryngology, and general surgery. He is credited for his no-touch technique and the invention of long-handled instruments, some of which are still in use today, to ...
Cowan, Scott W.   +4 more
core   +1 more source

Publication rates on the topic of racial and ethnic diversity in dermatology versus other specialties [PDF]

open access: yes, 2020
Background: The population of the U.S. is becoming more diverse every year. The field of dermatology is not following the same trend. Objective: To assess the promotion of diversity in the field of dermatology by analyzing publications focused on ...
Bray, Jeremy K   +3 more
core  

The association between patients' preferred treatment after the use of a patient decision aid and their choice of eventual treatment

open access: yesHealth Expectations, 2020
Objective To investigate the association between patients' preferred treatment and eventual treatment. Second, to compare patients with surgical treatment to watchful waiting in order to identify predictive factors for surgery.
Carmen S. S. Latenstein   +6 more
doaj   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Dehn surgery on knots in $S^3$ producing Nil Seifert fibred spaces [PDF]

open access: yes, 2014
We prove that there are exactly $6$ Nil Seifert fibred spaces which can be obtained by Dehn surgeries on non-trefoil knots in $S^3$, with $\{60, 144, 156, 288, 300\}$ as the exact set of all such surgery slopes up to taking the mirror images of the knots.
Ni, Yi, Zhang, Xingru
core   +1 more source

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