Results 41 to 50 of about 2,435,192 (345)

Pain management in surgical patients [PDF]

, 2011
Acute post-operative pain is a major problem which is not well addressed clinically; with patients regularly reporting significant pain following surgery (Clark, 2006). The possible harmful effects of untested surgical pain include: deep vein thrombosis,
Bonnell, Shanna R.
core  

Anesthesia in the surgery of strabismus: role of anesthetic agents in the ocular deviation and surgical outcome [PDF]

, 2015
Purpose: To determine whether the changes in the ocular alignment following general anesthesia, maintained with two different inhalational anesthetic agents, sevoflurane and desflurane, can be used as a predictor for surgical outcomes in children with ...
Arrico, Loredana, Cannata, Riccardo, Collini, Saul, Malagola, Romualdo, Migliorini, Raffaele, Servidio, Annalisa   +5 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Frequency of Predisposing Factor of Nausea and Vomiting After Chest Surgery Under General Anaesthesia [PDF]

, 2019
Background: Postoperative nausea and vomiting are common and distressing postsurgical symptoms. These symptoms are of particular concern in outpatient surgery because they may require additional direct resources, such as supplies and antiemetic ...
Bhatti, S. U. (Sami), Hanif, A. (Asif), Rehman, U. A. (Usman), Shahnawaz, A. (Ayesha), Ulhaq, Z. (Zabinfat), Ullah, Q. (Qudrat)   +5 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Comparison of high uterosacral and sacrospinous ligament suspension surgeries for the treatment of pelvic organ prolapse in women

Advanced Biomedical Research, 2023
Background: Pelvic floor disorders include urinary incontinence, fecal incontinence, and pelvic floor prolapse, which are common complaints in women. Patients that suffer from uterine prolapse could benefit from surgical procedures that stabilize pelvic ...
Maryam Hajhashemi, Aazam Zafarbakhsh, Minoo Movahedi, Aryan Rafieezadeh, Behnaz Sattari Rizi   +4 more
doaj   +1 more source

Optimizing the integration of advanced practitioners in a department of surgery: An operational improvement model [PDF]

, 2018
Physician assistants (PAs) and nurse practitioners (NPs) have established themselves as key members of the healthcare team to supplement practicing physicians in patient care.
Dunnington, Gary, Hockaday, Melissa, Smith, Cecelia, Torbeck, Laura J.   +3 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Epidemiological aspects of surgical site infections in an income country. The case of regional hospital center, Borgou (Benin) [PDF]

, 2017
Background: Surgical site infection is frustrating for the care team and depressing for the patient. Objective: To determine the epidemiological aspects of surgical site infections in regional hospital, Borgou.
Akpata, Robert, Allodé S., Alexandre, And Mêhinto K., Delphin, Atakpa S., Felix, Dadjo A., Yves, Fatigba O., Holden, Hodonou M., Adrien, Hounkponou-ahouingnan, Fanny, Mensah Ad, Emile, Tamou-sambo, Bio, Tobome, SEMEVO ROMARIC   +10 more
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Possible Skull Base Erosion After Prolonged Frontal Sinus Stenting [PDF]

, 2019
Frontal sinus stenting is widely used with the goal of maintaining nasofrontal duct patency after sinus surgery. The general recommendation is to leave stents in place for 6 months; however, prolonged stenting up to 6 years has been reported with no ...
Ching, Harry H., MD, Kim, Yuna, MD, Reeve, Nathaniel H., MD, Schroeder, Walter W., MD   +3 more
core   +2 more sources