Results 51 to 60 of about 2,358,271 (346)

Inefficiency in Delivery of General Surgery to Black Patients: A National Inpatient Sample Study

open access: yesThe Surgery Journal, 2023
Background Racial disparities in outcomes among patients in the United States are widely recognized, but disparities in treatment are less commonly understood. This study is intended to identify treatment disparities in delivery of surgery and
John N. Bliton
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Applications of controlled surgery in dimension 4: Examples

open access: yes, 2006
The validity of Freedman's disk theorem is known to depend only on the fundamental group. It was conjectured that it fails for nonabelian free fundamental groups. If this were true then surgery theory would work in dimension four.
Hegenbarth, Friedrich, Repovš, Dušan
core   +1 more source

Characterizing slopes for torus knots [PDF]

open access: yes, 2012
A slope $\frac pq$ is called a characterizing slope for a given knot $K_0$ in $S^3$ if whenever the $\frac pq$-surgery on a knot $K$ in $S^3$ is homeomorphic to the $\frac pq$-surgery on $K_0$ via an orientation preserving homeomorphism, then $K=K_0$. In
Ni, Yi, Zhang, Xingru
core   +1 more source

Comparison of high uterosacral and sacrospinous ligament suspension surgeries for the treatment of pelvic organ prolapse in women

open access: yesAdvanced Biomedical Research, 2023
Background: Pelvic floor disorders include urinary incontinence, fecal incontinence, and pelvic floor prolapse, which are common complaints in women. Patients that suffer from uterine prolapse could benefit from surgical procedures that stabilize pelvic ...
Maryam Hajhashemi   +4 more
doaj   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

open access: yesMolecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha   +10 more
wiley   +1 more source

Implementation of a Standardized Handoff System for a General Surgery Residency Program [PDF]

open access: yes, 2017
Introduction: The I-PASS Handoff Bundle is an evidence based standardized set of educational materials designed to decrease handoff failures in patient care. Two of every three sentinel events , the most serious events reported to the Joint Commission,
Brown, A. M.   +6 more
core   +1 more source

Comparison of Clinical Outcomes of Gripping Surface Technology Staple Reloads versus Standard Staple Reloads Used with Manual Linear Surgical Staplers

open access: yesMedical Devices: Evidence and Research, 2022
Stephen P Fortin,1 William Petraiuolo,2 Guy Cafri,1 Gustavo Scapini,3 Pratyush Agarwal,4 Divya Chakke,4 Stephen Johnston,1 Barbara H Johnson,1 Paul M Coplan,1,5 Shumin Zhang1 1MedTech Epidemiology and Real-World Data Science, Office of the Chief Medical ...
Fortin SP   +9 more
doaj  

Thrombosed capillary network in a full‐thickness burn

open access: yesClinical Case Reports, 2020
Full‐thickness burns are associated with cardinal clinical features. The recognition of these signs has important implications for immediate and future care of such burns.
Sharon Kennedy, Kevin C. Cahill
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

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