Results 71 to 80 of about 2,458,127 (294)

Who should perform thyroid surgery and who should not?

open access: yesTurkish Archives of Otorhinolaryngology, 2007
This report was prepared to • clarify the markedly increased disputes between the General Surgery Departments and Otorhinolaryngology-Head and Neck Surgery (ORL-HNS) Departments in respect to thyroid surgery, • to discuss the subject in question in ...
Levent Erişen   +2 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Screening for negative emotions and analysis of related factors among general surgery inpatients: a retrospective cross-sectional study

open access: yesFrontiers in Psychology
BackgroundAdverse psychological states in surgical patients can impact outcomes. This study aimed to evaluate mood disorders and associated factors in general surgery inpatients using the Huaxi Emotional Distress Index (HEI).MethodsThis retrospective ...
Jie Yang   +10 more
doaj   +1 more source

A Brief Overview of the Life and Work of Lyon Henry Appleby, M.D. (1895-1970). [PDF]

open access: yes, 2016
The life and work of Dr. Lyon Henry Appleby, M.D., portrays the essence of a devoted clinician committed to scholarly excellence. Born in Deseronto, Ontario, in 1895 and passing in 1970, Dr.
Cowan, Scott W.   +3 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Change in bowel habit, abdominal pain, and a palpable abdominal mass in a 58‐year‐old female

open access: yesClinical Case Reports, 2017
Key Clinical Message Giant colonic diverticulum is a rare complication of diverticulosis, which may present in the acute or chronic setting. Colonic resection and en bloc resection of the diverticulum are the favored management, however, conservative ...
Julian Peacock, Zane Perkins
doaj   +1 more source

Surgeon Speaks [PDF]

open access: yes, 2017
Like every surgeon, I started my residency training in General Surgery. Then I specialized in Thoracic and Cardiovascular Surgery and finally sub-specialized with a Fellowship in Heart and Lung Transplantation and Adult Cardiac Surgery at Duke University

core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Mechanisms and Nanomedicine Interventions of Acute Lung Injury Induced by Intestinal Ischemia-Reperfusion: A Mini Review

open access: yesInternational Journal of Nanomedicine
Guangyao Li,1– 3,* Binghui Jin,3,* Jialin Zhou,3,* Tao Sun,1 Shuang Wang,4 Zhe Fan2,3 1Department of Oncology, Cancer Hospital of Dalian University of Technology, Shenyang, People’s Republic of China; 2Department of General ...
Li G   +5 more
doaj  

Emergency Urological Surgery Performed by General Surgeons: A Systematic Review

open access: yesSociété Internationale d’Urologie Journal
Background: Across the world, many populations have limited access to urology care resulting in local general surgeons performing emergency urology procedures.
Patrick Miao   +3 more
doaj   +1 more source

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