Results 81 to 90 of about 2,458,127 (294)

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

Cellular Heterogeneity and IL-17 Pathway Dynamics Reveal Insights into the Transition from Ulcerative Colitis to Colorectal Cancer Through scRNA-Seq Analysis

open access: yesJournal of Inflammation Research
Yaxian Li,1,* Ruochuan Sun,1,* Xiaodong Wang,2 Mengdi Ma,1 Huizhen Wang,1 Bo Yang,1 Yida Lu,3 Yongxiang Li1 1Department of General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of China; 2The ...
Li Y   +7 more
doaj  

Thrombosed capillary network in a full‐thickness burn

open access: yesClinical Case Reports, 2020
Full‐thickness burns are associated with cardinal clinical features. The recognition of these signs has important implications for immediate and future care of such burns.
Sharon Kennedy, Kevin C. Cahill
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

miR-424 Targets AKT3 and PSAT1 and Has a Tumor-Suppressive Role in Human Colorectal Cancer [Retraction]

open access: yesCancer Management and Research
Fang Y, Liang X, Xu J, Cai X. Cancer Manag Res. 2018;10:6537–6547. We, the Editors and Publisher of the journal Cancer Management and Research, have retracted the published article.
Fang Y, Liang X, Xu J, Cai X
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Reduction of the mortality to the General surgical department of General hospital Valjevo: Serbia [PDF]

open access: yesHospital Pharmacology, 2018
Introduction: The safety of surgical procedures has emerged as a significant global public health problem. Aim: In this study, an assessment was made of the mortality in the population of general surgical patients and is proposed to prevent the ...
Vuković Mira H., Ilić Vladan R.
doaj  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Visceral and Subcutaneous Fat Deposits Exhibit Distinct Roles in the Initiation and Progression of Breast Cancer

open access: yesBreast Cancer: Targets and Therapy
Yu Zhang,1,* Qi Li,2,* Li Zhao,3,* Yi Pang,2 Lin Li,2 Wei-Wei Niu,2 Yu Xing,2 Yu Liu,2 Fu-Quan Zhang,2 Yu-Chen Fan,2 Yuan-Yuan Bao,1 Chun-Wei Li,4 Kang Yu1 1Department of Clinical Nutrition, Peking Union Medical College Hospital ...
Zhang Y   +12 more
doaj  

Use of virtual reality in children undergoing surgery

open access: yesFrontiers in Pediatrics
ObjectiveEarly mobilization and exercise after surgery are very important to reduce the impact on respiratory system function. The aim of this study was to compare the effects of early mobilization with virtual reality and conventional physiotherapy ...
Sabiha Bezgin   +5 more
doaj   +1 more source

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