Results 101 to 110 of about 2,458,127 (294)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

General Surgery [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1995
C H, Organ, J M, Porter
openaire   +3 more sources

Impact of the COVID-19 Pandemic on Multidrug-Resistant Organism Infections in Infected Pancreatic Necrosis: A Post-Hoc Cohort Analysis

open access: yesInfection and Drug Resistance
Baiqi Liu,1– 4 Caihong Ning,1– 4 Jiarong Li,1– 4 Zefang Sun,1– 4 Chiayen Lin,1– 4 Xiaoyue Hong,1– 4 Rong Guo,1– 4 Lu Chen,1– 4 Dingcheng Shen,1– 4 Gengwen Huang1– 4 1Department of Pancreatic Surgery, Xiangya Hospital of Central South University, Changsha,
Liu B   +9 more
doaj  

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Effect of the Evidence-Based and Multidisciplinary Pain Management Program in Patients After Laparoscopic Hepatectomy: A Quasi-Experimental Study

open access: yesJournal of Pain Research
Xiuxiu Song,1 Yuping Liu,1 Jinnan Zou,2 Dan Zhang,2 Ting Bai,1 Zhengxiang Han,3 Yuqin Wang1 1Nursing Department, Affiliated Hospital of Xuzhou Medical University, XuZhou, JiangSu, People’s Republic of China; 2General Surgery, Affiliated Hospital of ...
Song X   +6 more
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Design and Implementation of a Training Programme for General Practitioners in Emergency Surgery and Obstetrics in Precarious Situations in Ethiopia. [PDF]

open access: yes
Médecins Sans Frontières (MSF) has been implementing medical assistance programs in Ethiopia since 1994, including the rehabilitation of health structures and the supply of drugs and medical equipment.
Sohier, N, Fréjacques, L, Gagnayre, R
core   +1 more source

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