Results 51 to 60 of about 81,012 (245)

Hyers-Ulam, Rassias, and Mittag-Leffler stability for quantum difference equations in β-calculus

Frontiers in Applied Mathematics and Statistics
This paper investigates first-order nonlinear quantum difference equations governed by a general β-difference operator, encompassing the Jackson q-difference and Hahn difference operators as special cases.
Dalal Marzouq AlMutairi, Chokri Chniti, Saleh M. Alzahrani   +2 more
doaj   +1 more source

Numerical Simulation of Molding Hele-Shaw Flow of Polymeric Liquid Crystals

Journal of Fluid Science and Technology, 2007
To develop a general-purpose program for predicting the molding flow of polymeric liquid crystals, we present a basic model and its computational procedure. The flow is modeled by the Transversely Isotropic Fluid theory, which is equivalent to the Leslie-
Shigeomi CHONO, Tomohiro TSUJI, Jianye SUN   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Theory of spike-train power spectra for multidimensional integrate-and-fire neurons

Physical Review Research, 2019
Multidimensional stochastic integrate-and-fire (IF) models are a standard spike-generator model in studies of firing variability, neural information transmission, and neural network dynamics.
Sebastian Vellmer, Benjamin Lindner
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Poincare gauge gravity from nonmetric gravity

Nuclear Physics B
We consider general linear gauge theory, with independent solder form and connection. These spaces have both torsion and nonmetricity. We show that the Cartan structure equations together with the defining equation for nonmetricity allow the mixed ...
James T. Wheeler
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Asymptotic solutions of forced nonlinear second order differential equations and their extensions

Electronic Journal of Differential Equations, 2007
Using a modified version of Schauder's fixed point theorem, measures of non-compactness and classical techniques, we provide new general results on the asymptotic behavior and the non-oscillation of second order scalar nonlinear differential equations on
Angelo B. Mingarelli, Kishin Sadarangani
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source