Results 111 to 120 of about 746,393 (307)

Internet Uses for General, Health-Related, and Smoking Cessation Information Seeking from Gender and Uses and Gratifications Frameworks

open access: yesInternational Journal of Communication, 2022
Informed by gender role framework and uses and gratifications theory, this study examines gender differences and factors associated with Internet use utilizing Health Information National Trends Survey data (N = 3,738).
Zhiwen Xiao, Jaesub Lee, Li Zeng
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Employing Interpretive Research to Build Theory of Information Systems Practice [PDF]

open access: yes, 2003
This paper provides guidance and an example for carrying out research using an interpretive framework. Until quite recently, there has been little available in the IS literature to guide the interpretive researcher to build theory of IS practice.
Rowlands, Bruce
core  

Non-Equilibrium Statistical Mechanics Inspired by Modern Information Theory

open access: yesEntropy, 2013
A collection of recent papers revisit how to quantify the relationship between information and work in the light of modern information theory, so-called single-shot information theory.
Oscar C. O. Dahlsten
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Statistical Entropy in General Equilibrium Theory [PDF]

open access: yes
This essay seeks to develop an integrated account of the workings of statistical mechanics and thermodynamics as a theory of economic equilibrium. It begins with a probabilistic description of general systems (made out of numerous elements), based on the
Panagis Liossatos
core  

Decision errors, legal uncertainty and welfare : a general treatment [PDF]

open access: yes, 2014
This paper provides a general treatment of the implications for welfare of legal uncertainty. We distinguish legal uncertainty from decision errors: though the former can be influenced by the latter, the latter are neither necessary nor sufficient for ...
Ulph, David Tregear   +2 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Information seeking behavior:what should a general theory look like [PDF]

open access: yes, 2000
A general theory of information seeking behaviour must include an outline of an evolutionary theory of how organisms have adapted their cognitive apparatus to the demands raised in order to cope with their environments.
Hjørland, Birger
core  

A Hierarchy of Information Quantities for Finite Block Length Analysis of Quantum Tasks [PDF]

open access: yes, 2013
We consider two fundamental tasks in quantum information theory, data compression with quantum side information as well as randomness extraction against quantum side information.
Hayashi, M   +3 more
core   +1 more source

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