Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du +4 more
wiley +1 more source
Applying molecular dynamics simulations to validate OCT1 substrates uncovers vitamin K1 as a high-affinity ligand. [PDF]
Mahgoub EO, Ali R, Samara A, Ramotar D.
europepmc +1 more source
Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley +1 more source
Schematic showing a stretchable triboelectric nanogenerator based on interlocked wavy architectures that uses EGaIn microflower‐embedded PVDF‐TrFE and Nylon‐6 nanofiber membranes. The multi‐petaled, electron‐rich EGaIn microflowers enhance interfacial polarization and capacitance, while the interlocked wavy architecture enlarges the effective contact ...
Qianqian Xu +12 more
wiley +1 more source
Design Rules for Controlling Connectivity, Topology, and Sorting Using Hydrogen-Bonded Pairs and Aromatic Components in Palladium(II)-Based Interlocked and Foldameric Systems. [PDF]
Algar JL, Smith JN, Preston D.
europepmc +1 more source
Protein Structure, Evolution and Regulation of CER3, a Core Enzyme Partitioning Carbon into Two Specific Wax Biosynthetic Pathways. [PDF]
Niu Q, Liu L, Liu C, Lü S, Zhang H.
europepmc +1 more source
Protein Aggregates as Drivers of Receptor Clustering and Pathological Signaling: A Framework Linking Extracellular Amyloid-β to Tau Dysregulation. [PDF]
Ratis RC, Bonini JS, Bold ABW.
europepmc +1 more source
Structure of the Beat-Side complex reveals their interaction is required for neuromuscular system wiring. [PDF]
Priest JM +8 more
europepmc +1 more source
Green Synthesis of Ultrathin MWW Zeolites With Tunable Al-T Sites Using Nitrogen-Free Secondary OSDAs for Catalytic Cracking. [PDF]
Zhang H +12 more
europepmc +1 more source

