Results 101 to 110 of about 179,210 (301)

Neoadjuvant toripalimab plus axitinib for clear cell renal cell carcinoma with inferior vena cava tumor thrombus: NEOTAX, a phase 2 study

open access: yesSignal Transduction and Targeted Therapy
The potential benefit of neoadjuvant toripalimab plus axitinib in cases with clear cell renal cell carcinoma (ccRCC) and inferior vena cava tumor thrombus (IVC-TT) remains unclear.
Liangyou Gu   +17 more
doaj   +1 more source

FomA‐Containing Outer Membrane Vesicles of Fusobacterium Nucleatum Facilitate Bladder Cancer Lymphatic Metastasis via IL‐6‐Dependent M2b Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
Urinary Fusobacterium nucleatum–derived outer membrane vesicles are shown to promote bladder cancer lymphatic metastasis. The vesicle protein FomA activates TLR2/NF‐κB signaling in tumor cells, induces IL‐6 secretion, and drives M2b macrophage polarization and VEGF‐C–dependent lymphangiogenesis, revealing a microbiota‐driven mechanism linking tumor ...
Wentai Shangguan   +17 more
wiley   +1 more source

Toward Prostate Cancer Early Warning with a Self‐Powered Wearable Biosensing Platform Integrated with Machine Learning

open access: yesAdvanced Science, EarlyView.
ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu   +10 more
wiley   +1 more source

Long-term complications of continent catheterizable channels: a problem for transitional urologists. [PDF]

open access: yes, 2018
A majority of the transitional urology patient population have neurogenic bladder and many of these patients have undergone creation of continent catheterizable channels (CCCs) to facilitate bladder emptying.
Baradaran, Nima   +2 more
core  

General Urology [PDF]

open access: yesPostgraduate Medical Journal, 1957
openaire   +2 more sources

Lesional volume in the prediction of clinically significant prostate cancer

open access: yesWorld Journal of Surgical Oncology
Background While MRI has significantly advanced risk stratification in prostate cancer, PIRADS scoring alone is still insufficient to solely determine which patients do not require biopsy.
Bellamy Brodie   +9 more
doaj   +1 more source

Role of Case-Based Discussion as Workplace-Based Assessment Tool in Urology and General Surgery

open access: yesJournal of Gandhara Medical and Dental Sciences
OBJECTIVES To determine the effectiveness of case-based discussion in terms of medical record-keeping, clinical reasoning, clinical judgment, and self-reflection in the management of patients. METHODOLOGY A multidisciplinary descriptive study was
Shimee Shahzadi   +4 more
doaj   +1 more source

A Conformal Wearable Ultrasound Bioelectronics for Mechanotherapy Reprogramming of Fibroblast Plasticity via Wnt‐FGF10 Axis to Overcome Fibrotic Healing in Urethral Regeneration

open access: yesAdvanced Science, EarlyView.
Fibrotic scarring persistently challenges urethral reconstruction. This study introduces a conformal, wearable ultrasound bioelectronic system that overcomes this by reprogramming fibroblast fate. The device activates a developmental Wnt–FGF10 axis, driving fibroblasts toward a regenerative FGF10+ phenotype that promotes angiogenesis and matrix ...
Mingming Yu   +7 more
wiley   +1 more source

Xanthogranulomatous pyelonephritis: presentation and management [PDF]

open access: yes, 2019
Xanthogranulomatous pyelonephritis (XGP) is characterized by the presence of lipid-laden foamy macrophages with both acute and chronic phase inflammatory cells.
Badiu, Dumitru Cristinel   +8 more
core   +1 more source

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