Results 121 to 130 of about 109,586 (295)

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

open access: yesAdvanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao   +7 more
wiley   +1 more source

General Urology [PDF]

open access: yesPostgraduate Medical Journal, 1957
openaire   +2 more sources

Cost‐effectiveness analysis of a biopsy‐free diagnostic strategy for prostate cancer using mpMRI and PSMA‐PET/CT

open access: yesBJUI Compass
Introduction Prostate‐Specific Membrane Antigen Positron Emission Tomography Computed Tomography (PSMA PET/CT) has shown a higher diagnostic accuracy in prostate cancer imaging when compared to conventional modalities, with improved sensitivity and ...
Joshua Yi Min Tung   +18 more
doaj   +1 more source

Herba Lysimachiae Polysaccharide‐Modified Selenium Nanoparticles Alleviate Oxidative Injury in Kidney Stones via TOMM22‐Regulated Mitophagy Activation

open access: yesAdvanced Science, EarlyView.
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang   +10 more
wiley   +1 more source

A prospective study using questionnaires and urodynamic assessments to evaluate bladder function and continence changes after robotic assisted radical prostatectomy

open access: yesScientific Reports
Post-prostatectomy continence status, in addition to lower urinary tract symptoms, is a major concern among patients after robotic-assisted radical prostatectomy (RaRP).
Ping-Hsuan Yu   +6 more
doaj   +1 more source

A novel approach to cystolithotripsy with suction under local Anaesthesia: A case series from a tertiary institution

open access: yesUrology Video Journal
Cystolithotripsy is a procedure performed for bladder stones that is typically done under general or regional anesthesia. This is a case series of cystolithotripsy done under local anesthesia with flexible cystoscopy and suction.A 71-year-old man with no
Julene Ong Hui Wun   +6 more
doaj   +1 more source

Urology /

open access: yes, 1987
"First printing"--T.p. verso.Shipping list no.: 88-654-P.Half title: Urology in World War II.Includes bibliographies and index.Mode of access ...
Patton, John F., 1903-   +2 more
core  

Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu   +26 more
wiley   +1 more source

Cleveland Clinic Akron General Urology Residency Program's COVID-19 Experience. [PDF]

open access: yesUrology, 2020
Vargo E   +6 more
europepmc   +1 more source

A look to the urology education and urology profession in Turkey: evaluation of survey results

open access: yes, 2010
Objective: To evaluate the aspects and thoughts of urology residents and new specialists about urology education and urology profession in Turkey. Materials and methods: Eighty three residents and new specialists were included in the survey.
Binbay, M.   +20 more
core   +1 more source

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