Results 121 to 130 of about 109,586 (295)
A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao +7 more
wiley +1 more source
Introduction Prostate‐Specific Membrane Antigen Positron Emission Tomography Computed Tomography (PSMA PET/CT) has shown a higher diagnostic accuracy in prostate cancer imaging when compared to conventional modalities, with improved sensitivity and ...
Joshua Yi Min Tung +18 more
doaj +1 more source
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang +10 more
wiley +1 more source
Post-prostatectomy continence status, in addition to lower urinary tract symptoms, is a major concern among patients after robotic-assisted radical prostatectomy (RaRP).
Ping-Hsuan Yu +6 more
doaj +1 more source
Cystolithotripsy is a procedure performed for bladder stones that is typically done under general or regional anesthesia. This is a case series of cystolithotripsy done under local anesthesia with flexible cystoscopy and suction.A 71-year-old man with no
Julene Ong Hui Wun +6 more
doaj +1 more source
"First printing"--T.p. verso.Shipping list no.: 88-654-P.Half title: Urology in World War II.Includes bibliographies and index.Mode of access ...
Patton, John F., 1903- +2 more
core
Renal IGFBP6 Interacts With THBS1 to Drive Renal Cellular Senescence and Fibrosis
ABSTRACT Epithelial dedifferentiation and myofibroblast activation are critical drivers of chronic kidney disease (CKD) progression. Elevated levels of IGFBP6 have been linked to decreased renal function in CKD patients, but its precise role and underlying mechanisms remain unclear.
Ju‐tao Yu +26 more
wiley +1 more source
Cleveland Clinic Akron General Urology Residency Program's COVID-19 Experience. [PDF]
Vargo E +6 more
europepmc +1 more source
A look to the urology education and urology profession in Turkey: evaluation of survey results
Objective: To evaluate the aspects and thoughts of urology residents and new specialists about urology education and urology profession in Turkey. Materials and methods: Eighty three residents and new specialists were included in the survey.
Binbay, M. +20 more
core +1 more source

