Results 141 to 150 of about 181,307 (301)

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Design Principles for Next Generation of Small Organic Molecules for Photodynamics Therapy Revealed by Nonadiabatic Molecular Dynamics

Chemistry – A European Journal, EarlyView.
Molecular design reshapes the landscape of excited‐state relaxation. Nonadiabatic dynamics reveal how electronic structure guides population flow between competing pathways beyond static energetic arguments. ABSTRACT Nitrobenzochalcogenadiazole derivatives are emerging candidates for photodynamic therapy (PDT), yet the precise mechanisms governing ...
Vinícius N. da Rocha, Davide Avagliano, Paulo C. Piquini   +2 more
wiley   +1 more source

The place of andrological cases in our general urology practice

Urology Research and Practice, 2019
Objective: In this study, it was aimed to analyze the diagnoses of patients who applied to urology clinic and to assess the severity and contribution of the andrology cases in our general urological practice.
Ayhan Karaköse, Turgut Alp, Numan Doğu Güner, Mehmet Behiç Çıtlak, Sabahattin Aydın   +4 more
doaj  

Medical image computing and computer-aided medical interventions applied to soft tissues. Work in progress in urology

, 2006
Until recently, Computer-Aided Medical Interventions (CAMI) and Medical Robotics have focused on rigid and non deformable anatomical structures. Nowadays, special attention is paid to soft tissues, raising complex issues due to their mobility and ...
Bart, Stéphane, Baumann, Michael, Berkelman, Peter, Bolla, Michel, Chartier-Kastler, Emmanuel, Cinquin, Philippe, Daanen, Vincent, Descotes, Jean-Luc, Dusserre, Andrée, Giraud, Jean-Yves, Leroy, Antoine, Long, Jean-Alexandre, Marchal, Maud, Moalic, Ronan, Mozer, Pierre, Payan, Yohan, Promayon, Emmanuel, Troccaz, Jocelyne, Voros, Sandrine   +18 more
core   +1 more source

Promoting Safe Opioid Disposal: Experimental Evidence on Behavioral Messaging With Financial Incentives

Health Economics, EarlyView.
ABSTRACT Some patients prescribed opioid pills fail to properly dispose of their unused pills, posing a risk for others. We report results from a pre‐registered field experiment testing whether behaviorally informed reminder cards increase participation in a financial incentive program for returning unused opioid pills among U.S. Veterans.
Mattie Toma, Russell Burnett, Pompa Debroy, Eugen Dimant, Jean Liu, Elana Safran, Uzaib Saya, Bill Schultz   +7 more
wiley   +1 more source

Erectile implants in female-to-male transsexuals: Our experience in 130 patients [PDF]

, 2008
BEYSENS, M, DECAESTECKER, K, HOEBELKE, P, LUMEN, N, Monstrey, Stan, OPDENAKKER, Y   +5 more
core   +2 more sources

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Patient Related Outcomes for Interstitial Cystitis/Bladder Pain Syndrome Recommendations for Clinical Trials and General Urology Practice. [PDF]

Neurourol Urodyn
Hayes B, Namugosa M, Evans RJ, Hajebrahimi S, Janssen D, King C, Pandey S, Curtis Nickel J.   +7 more
europepmc   +1 more source

Comparing the effectiveness of prostate cancer screening protocols: European Association of Urology– and European Randomized Study of Screening for Prostate Cancer–based strategies

International Journal of Cancer, EarlyView.
What's New? Although screening reduces prostate cancer mortality, concerns about overdiagnosis and unnecessary biopsies have given rise to more tailored strategies. The European Association of Urology (EAU) proposed a risk‐adapted screening strategy combining prostate‐specific antigen (PSA)‐based intervals, a risk calculator, and magnetic resonance ...
Zhenwei Yang, Luuk A. van Duuren, Monique J. Roobol, Nicole S. Erler, Dimitris Rizopoulos, Eveline A. M. Heijnsdijk   +5 more
wiley   +1 more source

Shifts in clinical practice and patient demographics following the introduction of holmium laser enucleation for benign prostatic hyperplasia in a general urology clinic. [PDF]

J Biol Methods
Choksi AU, Smani S, Lokeshwar SD, Sundaresan VM, Hayden CS, Segal DA, Kellner DS.   +6 more
europepmc   +1 more source