Results 101 to 110 of about 181,307 (301)

Neoadjuvant toripalimab plus axitinib for clear cell renal cell carcinoma with inferior vena cava tumor thrombus: NEOTAX, a phase 2 study

Signal Transduction and Targeted Therapy
The potential benefit of neoadjuvant toripalimab plus axitinib in cases with clear cell renal cell carcinoma (ccRCC) and inferior vena cava tumor thrombus (IVC-TT) remains unclear.
Liangyou Gu, Cheng Peng, Qiyang Liang, Qingbo Huang, Deqiang Lv, Houming Zhao, Qi Zhang, Yu Zhang, Peng Zhang, Shichao Li, Junnan Xu, Luyao Chen, Yongpeng Xie, Jinhang Li, Gang Guo, Xu Zhang, Baojun Wang, Xin Ma   +17 more
doaj   +1 more source

BUSM News and Notes [PDF]

, 1991
Monthly newsletter providing updates of interest to the Boston University School of Medicine ...
Boston University School of Medicine Office of Informational Services
core  

Piezo1 Channel Mediates Mechanically Programmable Drug Delivery to Potentiate Intravesical Chemotherapy

Advanced Science, EarlyView.
This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma, Xing Li, Minxuan Jing, Zezhong Yang, Jiale He, Jianpeng Li, Xiao Liang, Yunzhong Jiang, Rou Huang, Yuanquan Zhang, Yuanchun Pu, Jiawei Xiu, Yutong Chen, Kaibo Mi, Pu Zhang, Lei Wang, Jinhai Fan   +16 more
wiley   +1 more source

General Urology [PDF]

Postgraduate Medical Journal, 1957
openaire   +2 more sources

Lesional volume in the prediction of clinically significant prostate cancer

World Journal of Surgical Oncology
Background While MRI has significantly advanced risk stratification in prostate cancer, PIRADS scoring alone is still insufficient to solely determine which patients do not require biopsy.
Bellamy Brodie, Daniel Yang Yao Peh, Yu Guang Tan, Yan Mee Law, Kae Jack Tay, Christopher Wai Sam Cheng, Henry Sun Sien Ho, John Shyi Peng Yuen, Alvin Yuan Ming Lee, Kenneth Chen   +9 more
doaj   +1 more source

Role of Case-Based Discussion as Workplace-Based Assessment Tool in Urology and General Surgery

Journal of Gandhara Medical and Dental Sciences
OBJECTIVES To determine the effectiveness of case-based discussion in terms of medical record-keeping, clinical reasoning, clinical judgment, and self-reflection in the management of patients. METHODOLOGY A multidisciplinary descriptive study was
Shimee Shahzadi, Muhammad Shah, Liaqat Ali, Humera Adeeb, Brekhna Jamil   +4 more
doaj   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

Cost‐effectiveness analysis of a biopsy‐free diagnostic strategy for prostate cancer using mpMRI and PSMA‐PET/CT

BJUI Compass
Introduction Prostate‐Specific Membrane Antigen Positron Emission Tomography Computed Tomography (PSMA PET/CT) has shown a higher diagnostic accuracy in prostate cancer imaging when compared to conventional modalities, with improved sensitivity and ...
Joshua Yi Min Tung, Rachel Shu‐En Lau, Edmund Pek Siang Teo, Kit Mun Chow, Julene Hui Wun Ong, Timothy Siliang Lu, Weiren Chen, Jingqiu Li, Xinyan Yang, Alvin Yuanming Lee, Yu Guang Tan, Kae Jack Tay, Sue Ping Thang, Winnie Wing Chuen Lam, Yan Mee Law, Henry Sun Sien Ho, Christopher Wai Sam Cheng, John Shyi‐Peng Yuen, Kenneth Chen   +18 more
doaj   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

Advanced Science, EarlyView.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou, Ke Li, Xuelan Li, Lei Yi, Zhengxiang Wang, Huan Ding, Sheng Wu, Feiyu Liu, Yuan Li, Rui Cheng, Jianliang Shen   +10 more
wiley   +1 more source

A prospective study using questionnaires and urodynamic assessments to evaluate bladder function and continence changes after robotic assisted radical prostatectomy

Scientific Reports
Post-prostatectomy continence status, in addition to lower urinary tract symptoms, is a major concern among patients after robotic-assisted radical prostatectomy (RaRP).
Ping-Hsuan Yu, Chih-Chieh Lin, Hsiao-Jen Chung, Tzu-Ping Lin, Eric Yi-Hsiu Huang, Tzu-Hao Huang, William J. Huang   +6 more
doaj   +1 more source