The power of microRNA regulation—insights into immunity and metabolism
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto+2 more
wiley +1 more source
EVALUATION OF DISASTER MITIGATION SYSTEM AGAINST LAHAR FLOW OF PUTIH RIVER, MT. MERAPI AREA
Merapi mount lies in the border of Yogyakarta and Central Java province. It frequently produces lava sediment deposit in the upper part of the mount, or is called as lava dome.
T. Maksal Saputra
doaj +1 more source
A stepwise emergence of evolution in the RNA world
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Stone Finials in Ottoman Period Religious Buildings in Bitola, Ohrid, and Skopje Cities of Macedonia
Finials, observed in Anatolia since 7000 B.C., have been used in various religions and societies in different forms and symbolic meanings, and have been applied by Turks with great success above the tents and building tops and on spearheads.
Gülşen Dişli, Nurcan İnci-Fırat
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Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel+2 more
wiley +1 more source
Collected works of Dorothy Crowfoot Hodgkin. Vol. I. Insulin. Vol. II. Cholestrol, penicillin and other antibiotics. Vol. III. General crystallography and essaysedited by G. G. Dodson, J. P. Glusker, S. Ramaseshan and K. Venkatesan [PDF]
R. F. Bryan
+6 more sources
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Flood Disaster Mitigation as Revealed by Cawang-Manggarai River Improvement of Ciliwung River
Ciliwung River that flows from Bogor highland is one of the rivers traversing several lowlands in Jakarta. Having the lowland topographic condition, the area along Ciliwung River is potentially inundated.
Airlangga Mardjono
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Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Health, work and the general practitioner [PDF]
Thorley, K Hussey, L Agius, R Editorial England Occupational medicine (Oxford, England) Occup Med (Lond). 2008 Jun;58(4):233-5.
Louise Hussey+2 more
openaire +3 more sources