Results 61 to 70 of about 870,132 (295)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Social Work in General Practice [PDF]

open access: yesBMJ, 1958
Considerable interest to-day is focused on the treat ment and management of stress and strain and emotional disturbance in general practice. Opinions vary regarding the extent and importance of this prob lem, but few would deny that the family doctor, whether he likes it or not, is faced with a variety of social and emotional problems on which patients
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Hanford Works Report HW-27229

open access: yes, 1953
Purpose: "The Hanford Works Analytical Manual for Process Water is designed to specify the analytical methods to be applied for control purposes in the Reactor Section, Process Sub-Section laboratories.
Hanford Works
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Titles of Works, not included in the General bibliography

open access: yesBothalia: African Biodiversity & Conservation, 1950
No Abstract ...
Ethel M. Doidge
doaj   +1 more source

UMPSA receives visit from Director-General of Public Works [PDF]

open access: yes
PEKAN, 26 January 2025 – Universiti Malaysia Pahang Al-Sultan Abdullah (UMPSA) received a visit from the Director-General of Public Works, Datuk Wira Ir.
Naqiah, Puaad
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The use of rapid assessment for flood hazard map development in upper citarum river basin

open access: yesMATEC Web of Conferences, 2018
Flood is a natural disaster that can occur at any time and anywhere. The flood disaster causes material and non-material loss, then in order to increase the resilience to disaster, an early warning system is needed.
Moe Idham Riyando   +4 more
doaj   +1 more source

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