Results 61 to 70 of about 728,983 (245)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Public Values in Water Law: A Case of Substantive Fragmentation?
Utrecht Law Review, 2014 Horizontal fragmentation, from a public-values perspective, is a quite well-documented phenomenon in international (water) law. However, the literature does not provide any insight into vertical or substantive fragmentation, i.e.
Monika Ambrus +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hydrodynamic Modeling for Enhance Water System in Katingan Tidal Lowlands
Jurnal Teknik PengairanA study was conducted on the Katingan tidal lowland area with hydro-topography A and B. The lowland area has good irrigation capability but low drainage capability, resulting in excessive inundation.
Insanul Kamil +3 more
doaj +1 more source
PSYCHIATRIC WARD IN GENERAL HOSPITAL: PROFESSIONALS VIEW WHO WORKS IN GENERAL HOSPITAL [PDF]
Revista Eletrônica de Enfermagem, 2003 The proposal of this study was the one of looking for the professionals of health that act in generalhospital, the perception and the acceptance of the same ones on the possible implantation of psychiatric beds inthe institution close to in that act. The
Jacó Fernando Schneider +1 more
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The hidden work of general practitioners: An ethnography
Social Science & MedicineHigh quality primary care is a foundational element of effective health services. Internationally, primary care physicians (general practitioners (GPs), family doctors) are experiencing significant workload pressures. How non-patient-facing work contributes to these pressures and what constitutes this work is poorly understood and often unrecognised ...
Rachel Barnard +5 more
openaire +4 more sources