Results 81 to 90 of about 6,428,375 (291)

Advantage through training? A microeconometric evaluation of the employment effects of active labour market programmes in Poland [PDF]

open access: yes
We estimate the employment effects of training, intervention works (subsidised employment), and public works programmes in Poland. The analysis is based on retrospective monthly calendar information on the labour force state and active labour market ...
Puhani, Patrick A.
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Willingness to Pay Additional Water Rate and Irrigation Knowledge of Farmers in Dinar Karakuyu Irrigation Areas in Turkey

open access: yesTurkish Journal of Agriculture: Food Science and Technology, 2017
Water which has become commodity product which is an important product today. Turkey is not a water rich country. In this study, agricultural enterprises in the field of Irrigation Project in Dinar Karakuyu which was implemented in 1992 by DSI. The study
Mevlüt Gül, Kutlan Uzunkaya
doaj   +1 more source

Generations at Work [PDF]

open access: yesAAOHN Journal, 2005
Sandy K. Calhoun, Patricia B. Strasser
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Public Values in Water Law: A Case of Substantive Fragmentation?

open access: yesUtrecht Law Review, 2014
Horizontal fragmentation, from a public-values perspective, is a quite well-documented phenomenon in international (water) law. However, the literature does not provide any insight into vertical or substantive fragmentation, i.e.
Monika Ambrus   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Hydrodynamic Modeling for Enhance Water System in Katingan Tidal Lowlands

open access: yesJurnal Teknik Pengairan
A study was conducted on the Katingan tidal lowland area with hydro-topography A and B. The lowland area has good irrigation capability but low drainage capability, resulting in excessive inundation.
Insanul Kamil   +3 more
doaj   +1 more source

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