Results 101 to 110 of about 13,654,241 (290)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Assessing Agricultural Reuse Potential of Treated Wastewater: A Hybrid Machine Learning Approach

Agronomy
Estimating the quality of treated wastewater is a complex, nonlinear challenge that traditional statistical methods struggle to address. This study introduces a hybrid machine learning approach to predict key effluent parameters from an advanced ...
Daniyal Durmuş Köksal, Yeşim Ahi, Mladen Todorovic   +2 more
doaj   +1 more source

[Carnegie Steel Co. (Bellaire Works), Engine Drawing Card, Sketch No. 6387]

, 1916
This engine drawing card was created for the Carnegie Steel Company, Bellaire Works, Class 4-20C. Section N 4C. Sketch 6387. Copy Spec.
Baldwin Locomotive Works
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

USING OF DERIVATE- GRAPHICAL ANALYSIS FOR INVESTIGATION OF EFFICIENCY OF EXOTHERMAL REACTIONS IN THE PROCESSES OF PROFITABLE FEEDING OF CASTING

Литьë и металлургия, 2009
It is determined that derivate-graphic analysis gives possibility to investigate efficiency of exothermal reactions in the process of profitable feeding of castings.
D. M. Kukuj, Ju. N. Fasevich, V. V. Shevchuk, A. I. Turok   +3 more
doaj  

Bologna Città 30. Experiences and perspectives

TeMA: Journal of Land Use, Mobility and Environment
Bologna is the first major Italian city to become a ‘30 km/h City’, following the example of many other European cities. Since its launch in 2022, the ‘Bologna Città 30’ Plan has marked the beginning of a technical process, culminating in the approval of
Valentina Orioli, Luca Bellinato, Cleto Carlini   +2 more
doaj   +1 more source

[Carnegie Steel Co. (Bellaire Works), Engine Drawing Card, Sketch No. 6416]

, 1916
This engine drawing card was created for the Carnegie Steel Company, Bellaire Works, Class 4-20C. Section N 4C. Sketch 6416. Copy Spec.
Baldwin Locomotive Works
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

[Baldwin Locomotive Works, Six-Coupled Locomotive, Stock]

Verso: Negative No. 9227, The Baldwin Locomotive Works, Six-coupled Locomotive, Class 6-38-D, 164, Built for Stock. Construction No.
Baldwin Locomotive Works
core