Results 101 to 110 of about 870,132 (295)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Hanford Works Report HW-19300

open access: yes, 1950
The following report describes the procedures developed for the x-ray photometric determination of uraniuim in metal oxides and sludge and compares results, precision, and length of time of analyses by the General Electric X-Ray Photometer with analyses ...
Lambert, M. C.
core  

The Performance Evaluation of Irrigation Efficiency, Managerial Effectiveness, and Water Economic Productivity in Consolidated Agricultural Lands: A Case Study of the Gündüzler Irrigation Scheme

open access: yesTurkish Journal of Agriculture: Food Science and Technology
This study evaluates the performance of the Gündüzler Irrigation Scheme, developed in a fully land-consolidated agricultural area in the Tepebaşı district of Eskişehir Province, with a focus on irrigation efficiency, managerial effectiveness, and the ...
Eray Harman, Belgin Çakmak
doaj   +1 more source

[Baltimore & Ohio R.R. Co., Road No. 1450]

open access: yes
Verso: Baldwin Locomotive Works, General dimensions of ...
Baldwin Locomotive Works
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Hanford Works Report HW-23332

open access: yes, 1951
A report which is the ninth report of the research and development activities of the radiological sciences department, Hanford Works, which includes some items charged to control but include for for general ...
Parker, H. M.
core  

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

[Ferrocarril Provincial de Buenos Aires (Argentine), Engine Drawing Card, Sketch No. 7883]

open access: yes, 1926
This engine drawing card was created for Compania General de Ferrocarriles en la Provincia de Buenos Aires, Class 12 30 1/4 D. Section H-12 1/4 D. Sketch 7883. Copy Spec. 26 F 235.
Baldwin Locomotive Works
core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

[Ferrocarril Provincial de Buenos Aires, Argentine, Engine Drawing Card, Sketch No. 7888]

open access: yes, 1927
This engine drawing card was created for Compania General de Ferrocarriles en la Provincia de Buenos Aires, Class 14 28 1/4 D. Section H-14 1/4 D. Sketch 7888. Copy Spec.
Baldwin Locomotive Works
core  

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