Results 111 to 120 of about 13,654,241 (290)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
[The Baldwin Locomotive Works, Road No. 24]
Verso: Negative No. 7276, The Baldwin Locomotive Works, Class 6-38-D, 111, Road No.
Baldwin Locomotive Works
core
[The Stanley Works New Britain, Conn., Engine Drawing Card, Sketch No. 8313]
, 1935 This engine drawing card was created for Stanley Works Inc., Class 6 48 D. Section J-6-D. Sketch 8313. Copy Spec. 35D57-36D31 Sk. mod.
Baldwin Locomotive Works
core
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
[Baldwin Locomotive Works, Diesel Electric Locomotive, Stock]
Verso: Negative No. 9552, The Baldwin Locomotive Works, Diesel-electric Locomotive, Class 12 (OE) 1000-1-CC, 1, Built for Stock, Construction No.
Baldwin Locomotive Works
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[Carnegie Steel Co., Schoen Steel Wheel Works, Engine Drawing Card, Sketch No. 6496]
, 1916 This engine drawing card was created for the Carnegie Steel Company, Schoen Steel Wheel Works, Class 6-34 D. Section N-6 D. Sketch 6496. Copy Spec.
Baldwin Locomotive Works
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Metalurgija, 2019 Three dimensional model of 350 MW utility boiler furnace was established by CFD to explore the combustion characteristics of pulverized coal at different O2 / CO2 ratios. The temperature field, sub-concentrations distributions, burner wall heat loads and
X. M. Wang, X. L. Wu, W. Q. Zhou
doaj
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source