Results 71 to 80 of about 6,428,375 (291)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Wavelength flattened directional couplers for mirrorsymmetric interferometers
In the context of guided optics, we derive, analytically and geometrically, a rigorous general criterion to design wavelength insensitive interferometers with mirror symmetry, which are needed for wavelength multiplexing/demultiplexing.
Cherchi, Matteo, Tormen, Maurizio
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
A story about standardization for design of glass works [PDF]
This contribution attempts to give an overview of the European standardization framework which is related to the design and calculation of glass works in buildings.
Belis, Jan +3 more
core
On the sectional curvature along central configurations
In this paper we characterize planar central configurations in terms of a sectional curvature value of the Jacobi-Maupertuis metric. This characterization works for the $N$-body problem with general masses and any $1/r^{\alpha}$ potential with $\alpha> 0$
Jackman, Connor, Meléndez, Josué
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The use of rapid assessment for flood hazard map development in upper citarum river basin
Flood is a natural disaster that can occur at any time and anywhere. The flood disaster causes material and non-material loss, then in order to increase the resilience to disaster, an early warning system is needed.
Moe Idham Riyando +4 more
doaj +1 more source
Titles of Works, not included in the General bibliography
No Abstract ...
Ethel M. Doidge
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

