Results 61 to 70 of about 117,067 (357)

A Foundation Model Based CT Biomarker for Non‐Invasive Prediction of Response to Neoadjuvant Immunochemotherapy in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
This study introduces a foundation model‐based biomarker for risk stratification of pathological response in non‐small cell lung cancer. A Vision Mamba super‐resolution model standardizes heterogeneous CT images. A multi‐task Swin Transformer then fine‐tunes a pre‐trained lung foundation model to jointly optimize tumor segmentation and response ...
Yanglan Xu, Shuchang Zhou, Qin Peng, Xiao Bao, Xiaodan Ye, Ahmet Görkem Er, Tong Tong, Mirabela Rusu, Yajia Gu, Mailin Chen, Jing Gong   +10 more
wiley   +1 more source

Evolution of generalist resistance to herbicide mixtures reveals a trade-off in resistance management [PDF]

, 2020
Intense selection by pesticides and antibiotics has resulted in a global epidemic of evolved resistance. In agriculture and medicine, using mixtures of compounds from different classes is widely accepted as optimal resistance management.
Lowe, C, Hicks, H, Helen L. Hicks, Onkokesung, N., Freckleton, R., Robert Edwards, Hicks, H., Childs, DZ, Hull, R. I., Crook, L, Lowe, C., Roland Beffa, Comont, D., Crook, L., Childs, D.Z., Dylan Z. Childs, Nawaporn Onkokesung, Hull, R, Childs, D., Comont, D, Richard Hull, Beffa, R., Paul Neve, Hull, R., Edwards, R., David Comont, Freckleton, RP, Neve, P., Laura Crook, Hicks, H.L., Edwards, R, Freckleton, R.P., Robert P. Freckleton, Onkokesung, N, Claudia Lowe, Neve, P, Beffa, R   +36 more
core   +1 more source

Deep Learning‐Assisted Design of Mechanical Metamaterials

Advanced Intelligent Discovery, EarlyView.
This review examines the role of data‐driven deep learning methodologies in advancing mechanical metamaterial design, focusing on the specific methodologies, applications, challenges, and outlooks of this field. Mechanical metamaterials (MMs), characterized by their extraordinary mechanical behaviors derived from architected microstructures, have ...
Zisheng Zong, Pu Wen, Zhiping Chai, Dunxuan Wu, Han Ding, Zhigang Wu   +5 more
wiley   +1 more source

Clinical decision support system using a machine learning model to assist simultaneous cardiopulmonary auscultation: Open-label randomized controlled trial

Digital Health
Background The utility of a clinical decision support system using a machine learning (ML) model for simultaneous cardiac and pulmonary auscultation is unknown. Objective This study aimed to develop and evaluate an ML system's utility for cardiopulmonary
Takanobu Hirosawa, Tetsu Sakamoto, Yukinori Harada, Kazuki Tokumasu, Taro Shimizu   +4 more
doaj   +1 more source

Automated Bacterial Identification and Morphological Feature Analysis in Low‐Dose Cryo‐EM Using YOLOv11

Advanced Intelligent Discovery, EarlyView.
AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula, Lynnicia N. Massenburg, Spenser R. Brown, Amber N. Bible, Chanda R. Harris, Lance X. Zhang, Kiara Parker, Scott T. Retterer, Jennifer L. Morrell‐Falvey, Rama K. Vasudevan, Alexis N. Williams   +10 more
wiley   +1 more source

Birds of Ponický kras (central Slovakia) during autumn migration: mist-netting data [PDF]

Tichodroma
The aim of the work is to evaluate the mist netting of birds during autumn migration in the area of Ponický kras (near Poniky village, central Slovakia).
Peter KAŇUCH, Benajmín JARČUŠKA, Vladimír HRÚZ, Andrea KAŇUCHOVÁ, Anton KRIŠTÍN   +4 more
doaj   +1 more source

The Meta-Organism Response of the Environmental Generalist Pocillopora damicornis Exposed to Differential Accumulation of Heat Stress

Frontiers in Marine Science, 2021
Coral bleaching events in the marine environment are now occurring globally, and the frequency and severity of these events are increasing. Critically, these events can cause the symbiosis between Symbiodiniaceae and their coral hosts to break down, but ...
Jessica L. Bergman, William Leggat, Tracy D. Ainsworth   +2 more
doaj   +1 more source

Implantation‐On‐Chip: An AI‐Based Platform for Monitoring the Embryo Trophoblast–Endometrial Stroma Cross Talk With Xenobiotics Interference

Advanced Intelligent Systems, EarlyView.
We present a novel AI‐integrated implantation‐on‐chip platform that enables mimicking and monitoring the maternal–fetal interactions at the early phases of human embryo implantation with high spatiotemporal resolution. The complexity of the trophoblast invasion process was addressed by conducting the analysis at global (rate of invasion) and local ...
Joanna Filippi, Valentina Lacconi, Arianna Mencattini, Micol Massimiani, Dolores Lobresca, Gaia Posanzini, Alessia Riccardi, Paola Casti, Michele D’Orazio, Gianni Antonelli, Giorgia Curci, Luisa Campagnolo, Eugenio Martinelli   +12 more
wiley   +1 more source

Clinical background factors affecting outcomes of Helicobacter pylori eradication therapy in primary care

Journal of General and Family Medicine, 2019
Objective Few studies have reported the influence of clinical background factors on the outcome of Helicobacter pylori eradication therapy in primary care practice.
Nozomi Yokota, Ryusuke Ae, Masaki Amenomori, Koji Kitagawa, Takuya Nakamura, Tetsuro Yokota, Kato Masato, Teppei Sasahara, Yuri Matsubara, Koki Kosami, Yoshikazu Nakamura   +10 more
doaj   +1 more source

The need for academic generalists

Molecular Biology of the Cell, 2011
Academia should be willing to shoulder some of the responsibility for the current dearth of new therapeutic drugs. Our research funding is predicated on the assumption that it will bring value to society, but our emphasis on scientific specialization hinders our ability to add value when a broader vision is required.
Kelly, Regis B., Crawford, Douglas
openaire   +2 more sources