Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang +13 more
wiley +1 more source
Identifying Sources of Disagreement: Generalizability Theory in Manual Annotation Studies
Computational Linguistics, 2021 Petra Saskia Bayerl, Karsten Ingmar Paul
doaj +1 more source
Which method is optimal for estimating variance components and their variability in generalizability theory? evidence form a set of unified rules for bootstrap method. [PDF]
PLoS One, 2023 Li G.
europepmc +1 more source
Boundary‐Dependent Sleep–Wake Dysregulation in Idiopathic Hypersomnia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Idiopathic hypersomnia (IH) presents with excessive daytime sleepiness (EDS) despite apparently preserved nocturnal sleep, challenging traditional models of hypersomnolence based on sleep loss or fragmentation. We aimed to test the hypothesis that EDS in IH reflects excessive stabilization of the sleep state, consistent with ...
Samantha Mombelli +13 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Blood biomarkers are increasingly critical for non‐invasive Alzheimer's Disease (AD) diagnostics and research but typically require on‐site processing. Remote point‐of‐care collection methods could enhance biomarker testing in clinical and research settings.
Sara Ho +9 more
wiley +1 more source
Acceptability of the 8-case objective structured clinical examination of medical students in Korea using generalizability theory: a reliability study [PDF]
J Educ Eval Health Prof, 2022 Park SY, Lee SH, Kim MJ, Ji KH, Ryu JH.
europepmc +1 more source
Utility of the APE2 Score as a Diagnostic Tool for Autoimmune Encephalitis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To retrospectively evaluate the diagnostic performance of the Antibody Prevalence in Epilepsy and Encephalopathy (APE2) score relative to clinician‐adjudicated autoimmune encephalitis (AE) and the Graus criteria in a tertiary neuroimmunology referral cohort, including antibody‐negative AE.
Bijoya Basu +3 more
wiley +1 more source
Temporal dynamics of emotional processing: Parsing trial-wise variance of the late positive potential using Generalizability Theory. [PDF]
Psychophysiology, 2023 Hill KE +5 more
europepmc +1 more source
Maximizing the coefficient of generalizability under the constraint of limited resources
generalizability theory, optimization of decision studies, optimization techniques,
S. Baas, T. Theunissen, P. Sanders
core +1 more source
Association Between Neurofilament Light Chain and Real‐World Ambulatory Function in Progressive MS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurofilament light chain (NfL) is a biomarker of neuroaxonal injury in multiple sclerosis (MS), yet associations with functional outcomes remain unclear. Longitudinal associations between serum NfL (sNfL) and daily step count (STEPS) from wearable devices were assessed in a large international progressive MS cohort.
Gabby B. Joseph +5 more
wiley +1 more source