Results 61 to 70 of about 55,986 (262)

Impact of ECG Dataset Diversity on Generalization of CNN Model for Detecting QRS Complex

IEEE Access, 2019
Detection of QRS complexes in electrocardiogram (ECG) signal is crucial for automated cardiac diagnosis. Automated QRS detection has been a research topic for over three decades and several of the traditional QRS detection methods show acceptable ...
Ahsan Habib, Chandan Karmakar, John Yearwood   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Meta Deep Reinforcement Learning-Based Link Adaptation for Cellular Networks

Tongxin xuebao
To address the stringent requirements for reliability and data rate in cellular networks, an efficient and highly generalizable link adaptation method was proposed.
YE Xiaowen, LIN Hengyi, WU Yi
doaj  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Consistent Augmentation Learning for Generalizing CLIP to Unseen Domains

IEEE Access
Domain generalization (DG) is a challenging transfer learning task focused on learning invariant knowledge from limited source domains, thereby enhancing generalization to the out-of-distribution data in unseen domains.
Qinan Xuan, Tianyuan Yu, Liang Bai, Yirun Ruan   +3 more
doaj   +1 more source

LLMs prompted for graphs: hallucinations and generative capabilities

Applied Network Science
Abstract Large Language Models (LLMs) are nowadays prompted for a wide variety of tasks. In this article, we investigate their ability in reciting and generating graphs. We first study the ability of LLMs to regurgitate well known graphs from the literature (e.g. Karate club or the graph atlas).
Gurvan Richardeau, Samy Chali, Erwan Le Merrer, Camilla Penzo, Gilles Trédan   +4 more
openaire   +2 more sources