Results 111 to 120 of about 1,925,469 (317)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

S-duality and the N=2 Lens Space Index

open access: yes, 2013
We discuss some of the analytic properties of lens space indices for 4d N=2 theories of class S. The S-duality properties of these theories highly constrain the lens space indices, and imply in particular that they are naturally acted upon by a set of ...
Razamat, Shlomo S., Yamazaki, Masahito
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Generalized Fredholm Operators [PDF]

open access: yesTransactions of the American Mathematical Society, 1976
Let X, Y be Banach spaces over either the real field or the complex field. A continuous linear operator will be called a generalized Fredholm operator if T ( X ) T(X) is closed in Y, and Ker T and Coker T are reflexive Banach spaces.
openaire   +2 more sources

Statistical approximation properties of λ-Bernstein operators based on q-integers

open access: yesOpen Mathematics, 2019
In this paper, we introduce a new generalization of λ-Bernstein operators based on q-integers, we obtain the moments and central moments of these operators, establish a statistical approximation theorem and give an example to show the convergence of ...
Cai Qing-Bo, Zhou Guorong, Li Junjie
doaj   +1 more source

Some results on C-normal operators [PDF]

open access: yesSurveys in Mathematics and its Applications, 2023
A bounded linear operator on a complex Hilbert space ℋ is a C-normal operator if there exists a conjugation C on ℋ such that CT* TC=TT* . This class of operators seems a natural generalization of C-symmetric operators on a Hilbert space.
Ismail Lakehal, Messaoud Guesba
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Generalized Baskakov-Beta Operators

open access: yesRocky Mountain Journal of Mathematics, 2009
Denote \[ C_{\gamma}[0,\infty):=\left\{ f\in C[0,\infty): f(t)=O(t^{\gamma}) \text{ as } t\to\infty \text{ for some } \gamma>0\right\}. \] For \(f\in C_{\gamma}[0,\infty)\) and \(\alpha>0\) consider the modified Baskakov-beta operators, introduced by Wang in 2005: \[ B_{n,\alpha}(f,x)= \sum_{k=0}^\infty p_{n,k,\alpha}(x)\int_0^\infty b_{n,k,\alpha}(t)f(
Gupta, Vijay, Aral, Ali
openaire   +4 more sources

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