Results 101 to 110 of about 79,064 (268)
Generalizations of orthogonal polynomials
, 2003 We give a survey of recent generalizations for orthogonal polynomials that were recently obtained. It concerns not only multidimensional (matrix and vector orthogonal polynomials) and multivariate versions, or multipole (orthogonal rational functions ...
Verdonk, Brigitte +4 more
core
On Some Generalizations of Hardy's Integral Inequality
, 1999 In this paper we establish some new generalizations of the Hardy's inequality by using a fairly elementary analysis. The inequalities given here contain in the special cases, some of the recent generalizations of Hardy's integral inequality appearing in ...
Pachpatte, B.G.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Consonant Generalizations Revisited
, 1986 It has been over twenty years Since Clymer published his pioneer phonic generalization study. In this study Clymer selected four widely used basal reader manuals from which he culled over 150 consonant and other word attack generalizations, including ...
Gates, Louis
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
, 2013 Logik är ett gammalt och kraftfullt verktyg för att föra korrekta resonemang och människor har under lång tid studerat och tillämpat olika logiska system. Dessa studier har till stor del fokuserat på logik som innefattar ett binärt sanningsbegrepp, det vill säga logik där en utsaga är antingen sann eller falsk. Givetvis är detta en väldigt begränsad vy
openaire +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source