Results 61 to 70 of about 79,064 (268)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Students' Understandings of Arithmetic Generalizations [PDF]

open access: yes, 2014
This study examines fourth graders' understandings of arithmetic generalizations, the general properties of arithmetic that hold true for all numbers.
Haldar, Lina Chopra
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

First-Countability and its generalizations

open access: yes, 2012
Not ...
Shrimali, Narendra P.
core  

Good Empirical Generalizations

open access: yes
As well as being generalizations based on repeated empirical evidence, good empirical generalizations have five other characteristics: scope, precision, parsimony, usefulness, and a link with theory.empirical generalizations, research methods, science ...
Patrick Barwise
core   +1 more source

Generalizations of 𝑀-groups

open access: yes, 1995
In this note we prove some generalizations of Taketa’s theorem on solvability of M-groups.
Yakov Berkovich
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Generalizations and Refinements of Hermite-Hadamard's Inequality

open access: yes, 2001
In this article, with the help of concept of the harmonic sequence of polynomials, the well known Hermite-Hadamard’s inequality for convex functions is generalied to the cases with bounded derivatives of n-th order, including the so-called n-convex ...
Qi, Feng, Yang, Qiao, Wei, Zong-Li
core  

GENERALIZING [PDF]

open access: yesAJN, American Journal of Nursing, 1913
n ...
openaire   +1 more source

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