Results 91 to 100 of about 66,574 (258)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Kuwait Journal of Science, 2017 Relationship between plant species response and environmental gradients is becoming a challenging question in Ecology. A study was carried out along the roadsides of Wah Cantt.
Hafsa Bashir Bashir +2 more
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Diabetes, Metabolic Syndrome and Obesity, 2021 Qing Sun,1,2 Liang Tang,2 Qiurong Zeng,2 Mingjun Gu2 1Department of Clinical Nutrition, Fuling Center Hospital of Chongqing City, Chongqing, 408000, People’s Republic of China; 2Department of Endocrinology, Fuling Center Hospital of Chongqing City,
Sun Q, Tang L, Zeng Q, Gu M
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Relationships between site index modeling of crimean juniper and habitat factors
Kuwait Journal of ScienceThe aim of this study is to examine the relationships between height growth and some site factors of Crimean juniper in southwestern Anatolia. The data was collected from 130 sample plots selected from 10 districts in western Anatolia. The age and height
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Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Journal of Dairy Science: This study investigated the pattern of 6 behavioral parameters in Holstein dairy cows under heat stress (HS) conditions using a generalized additive mixed model (GAMM) statistical approach, while also evaluating the effectiveness of a commercial ...
C. Ferrari +5 more
doaj +1 more source