Results 91 to 100 of about 261,260 (312)

Time‐Dependent Therapeutic Effect of S‐Ketamine on PTSD Mediated by VTA‐OFC Dopaminergic Neurocircuit

Advanced Science, EarlyView.
This study reveals that early rather than late administration of S‐ketamine can ameliorate PTSD symptoms. This phenomenon is attributed to reversing the progressive inhibition of VTADA neurons and the function of VTADA‐OFC circuit following stress. Targeted stimulation of the OFC by TI‐NIBS to enhance DA release effectively extends the therapeutic time
Ye Wang, Lei Liu, Jinghao Wang, Jiannan Li, Huiming Li, Rui Wang, Hui Wang, Min Wang, Quanying Liu, Zhongmin Fan, Yunyun Zhang, Xinxin Zhang, Dan Wang, Sa Wang, Rou Xue, Jindong Mao, Min Cai, Pengfei Wei, Hailong Dong, Yumei Wu, Guangchao Zhao   +20 more
wiley   +1 more source

The Relationship between Metacognition, Rumination, and Sleep in University Students with a Tendency toward Generalized Anxiety Disorder

Behavioral Sciences
People with generalized anxiety disorder tend to have sleep problems, and studies have found correlations between metacognition, rumination, and sleep, but it is unclear how metacognition and rumination work in people with a tendency towards generalized ...
Hui Yu, Zhanbiao Shi, Mei Zhao
doaj   +1 more source

MIRTAZAPINE-INDUCED HYPONATREMIA IN A PATIENT WITH SYSTEMIC MASTOCYTOSIS AND GENERALIZED ANXIETY DISORDER

, 2023
Branislav Šakić, Alen Greš, Zoran Gajic   +2 more
openalex   +1 more source

Supported internet-delivered cognitive behavioral therapy programs for depression, anxiety, and stress in university students: open, non-randomised trial of acceptability, effectiveness, and satisfaction [PDF]

, 2018
BACKGROUND: Many university campuses have limited mental health services that cannot cope with the high demand. One alternative is to use internet-delivered cognitive behavioral therapy (iCBT) as a way of tackling barriers such as lack of availability ...
Coudray, Carissa, Frazier, Patricia, Hofmann, Stefan G., Palacios, Jorge E., Palmer, Riley, Palmieri, Patrick A., Richards, Derek   +6 more
core   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Hubungan Jenis Kelamin, Status Pernikahan, dan Status Pekerjaan dengan Gangguan Ansietas Menyeluruh di Klinik Psikiatri RS dr. Pirngadi Medan

Majalah Kedokteran Bandung, 2014
Generalized anxiety disorder constitutes a substantial proportion of the global burden of disease and is projected to be the second most common cause of disability by 2020. This disorder leads to increased distress and impaired life functions.
Nining Gilang Sari, Elmeida Effendy, Mustafa Mahmud Amin   +2 more
doaj   +1 more source

How should we treat major depression combined with anxiety? [PDF]

, 2007
One approach is to use antidepressants alone, which reduce symptoms for patients with major depression plus symptoms of anxiety or major depression plus generalized anxiety disorder.
Kelsberg, Gary, St. Anna, Leilani, Trotter, Bonnie   +2 more
core  

Cigarette smoking, nicotine dependence and anxiety disorders : a systematic review of population-based, epidemiological studies [PDF]

, 2012
Background Multiple studies have demonstrated that rates of smoking and nicotine dependence are increased in individuals with anxiety disorders. However, significant variability exists in the epidemiological literature exploring this relationship ...
A Bernstein, A Mykletun, A Schumann, AH Glassman, American Psychiatric Association, B Grant, B Isensee, BF Grant, BF Grant, C Coddou, CB Nelson, CD Morris, D Carroll, D Lawrence, D Lawrence, D Watson, DB Kandel, DB Kandel, DF Klein, DG Byrne, E Costello, EJ Costello, EO Johnson, F Cosci, FC Bandiera, Felice N Jacka, FL Lopes, GC Patton, H Orvaschel, H Sonntag, HJ Grabe, HU Wittchen, J Swendsen, JC Beckham, JD Kassel, JG Johnson, JR Cougle, JR Hughes, Julie A Pasco, K Lasser, KA Perkins, KC Koenen, KJ Ameringer, KL Chou, KR Merikangas, L Degenhardt, L Dierker, L Robins, LC Dierker, LC Masse, LJ Woodward, M Amering, M Farrell, M Jamal, M Preter, M Tobias, M Van Ameringen, M Zvolensky, MB Stein, Michael Berk, MJ Zvolensky, MJ Zvolensky, MJ Zvolensky, MJ Zvolensky, MJ Zvolensky, MM Schaap, MV Mendlowicz, N Breslau, N Breslau, N Breslau, N Breslau, N Breslau, N Breslau, N Breslau, N Schmitz, O Vesga-Lopez, P Cuijpers, P Wu, PG Van der Velden, PM McEvoy, R Acierno, R Pohl, RA Acierno, RA Brown, RC Gwynn, RC Kessler, RD Goodwin, RD Goodwin, S Baker-Morissette, S Bejerot, S Bejerot, S Schneider, S Tilley, SA Khuder, SB Morissette, SD Iniguez, SS Fu, Steven Moylan, T Tjora, TB Baker, U Hapke, U John, UN Durai, W Op Den Velde, World Health Organization   +104 more
core   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source

Cortico‐Striatal‐Midbrain Circuit Dysregulation Underlying MK‐801 Induced Impulsivity and the Ameliorative Effects of SEP

Advanced Science, EarlyView.
Impulsivity is a symptom across multiple psychiatric disorders, yet its neural basis remains elusive. This study shows that the NMDAR antagonist MK‐801 elevates dopamine release and disrupts neuronal selectivity in the nucleus accumbens, leading to impulsive behavior.
Xueru Wang, Qinyu Li, Zijie Li, Xuejiao Wang, Hui Yuan, Pingting Yang, Ling Qin   +6 more
wiley   +1 more source