Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
A Generalized Deep Learning Pipeline for Stain-Invariant Ultrastructural Segmentation in Peripheral Nerves. [PDF]
Borisovs V, Cavaletti G.
europepmc +1 more source
Physics‐Embedded Neural Network: A Novel Approach to Design Polymeric Materials
Traditional black‐box models for polymer mechanics rely solely on data and lack physical interpretability. This work presents a physics‐embedded neural network (PENN) that integrates constitutive equations into machine learning. The approach ensures reliable stress predictions, provides interpretable parameters, and enables performance‐driven, inverse ...
Siqi Zhan +8 more
wiley +1 more source
Generalized predictive control based on interval gray model with adaptive buffer operator for pattern-moving systems. [PDF]
Li N, Xu Z, Li X.
europepmc +1 more source
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu +14 more
wiley +1 more source
Fixed-point topology meets fractal memory: a Kutumba-stabilized framework for nonlocal fractal-fractional dynamics. [PDF]
Devi RA +6 more
europepmc +1 more source
Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu +5 more
wiley +1 more source
Bounds for survival probabilities in supercritical Galton-Watson processes and applications to population genetics. [PDF]
Bürger R.
europepmc +1 more source
ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray +3 more
wiley +1 more source

