Results 61 to 70 of about 26,636 (265)

Superstability of Generalized Higher Derivations

open access: yesAbstract and Applied Analysis, 2011
We define the notion of an approximate generalized higher derivation and investigate the superstability of strong generalized higher derivations.
T. L. Shateri
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Lie Derivations on Generalized Matrix Algebras by Local Actions

open access: yesAxioms
Let G=G(A,B,M,N) be a generalized matrix algebra. A linear map Δ:G→G is called a Lie derivation at E∈G if Δ([U,V])=[Δ(U),V]+[U,Δ(V)] for all pairs U,V∈G such that UV=E.
Jinhong Zhuang, Yanping Chen, Yijia Tan
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

Action of multiplicative (generalized)-derivations and related maps on square closed Lie ideals in prime rings

open access: yesМатематичні Студії
Let $\mathcal{R}$ be a prime ring and $L$ a nonzero square closed Lie ideal of $\mathcal{R}$. Suppose $F,G,H\colon \mathcal{R}\to \mathcal{R}$\break are three multiplicative (generalized)-derivations associated with the maps $\delta,g, h\colon \mathcal{R}
B. Dhara
doaj   +1 more source

Generalized Toda theory from six dimensions and the conifold

open access: yesJournal of High Energy Physics, 2017
Recently, a physical derivation of the Alday-Gaiotto-Tachikawa correspondence has been put forward. A crucial role is played by the complex Chern-Simons theory arising in the 3d-3d correspondence, whose boundary modes lead to Toda theory on a Riemann ...
Sam van Leuven, Gerben Oling
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Stability and Superstability of Generalized (𝜃, 𝜙)-Derivations in Non-Archimedean Algebras: Fixed Point Theorem via the Additive Cauchy Functional Equation

open access: yesJournal of Applied Mathematics, 2011
Let 𝐴 be an algebra, and let 𝜃, 𝜙 be ring automorphisms of 𝐴. An additive mapping 𝐻∶𝐴→𝐴 is called a (𝜃,𝜙)-derivation if 𝐻(𝑥𝑦)=𝐻(𝑥)𝜃(𝑦)+𝜙(𝑥)𝐻(𝑦) for all 𝑥,𝑦∈𝐴.
M. Eshaghi Gordji   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

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