Results 51 to 60 of about 94,501 (272)

Generalized Number Derivatives

open access: yes, 2005
We generalize the concept of a number derivative, and examine one particular instance of a deformed number derivative for finite field elements. We find that the derivative is linear when the deformation is a Frobenius map and go on to examine some of its basic properties.
openaire   +3 more sources

On generalized Peano derivatives [PDF]

open access: yesTransactions of the American Mathematical Society, 1983
A function F F is said to have a generalized n n th Peano derivative at x x if F F is continuous in a neighborhood of x x and if there exists a positive integer k k such that a k k th primitive of F F in the ...
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Generalized derivations with central values on lie ideals LIE IDEALS [PDF]

open access: yes, 2014
Let R be a prime ring of H a generalized derivation and L a noncentral lie ideal of R. We show that if l^sH(l)l^t in Z(R) for all lin2 L, where s, t> 0 are fixed integers, then H(x) = bx for some b in C, the extended centroid of R, or R satisfies S4 ...
Rahmani, Venus, Sahebi, Shervin
core  

GENERALIZED HIGHER DERIVATIONS [PDF]

open access: yesBulletin of the Australian Mathematical Society, 2012
AbstractA type of generalized higher derivation consisting of a collection of self-mappings of a ring associated with a monoid, and here called a D-structure, is studied. Such structures were previously used to define various kinds of ‘skew’ or ‘twisted’ monoid rings. We show how certain gradings by monoids define D-structures.
E. P. COJUHARI, B. J. GARDNER
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Generalized Derivations of Prime Rings

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2007
Let R be an associative prime ring, U a Lie ideal such that u2∈U for all u∈U. An additive function F:R→R is called a generalized derivation if there exists a derivation d:R→R such that F(xy)=F(x)y+xd(y) holds for all x,y∈R. In this paper, we prove that
Huang Shuliang
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Local Generalized (α,β)-Derivations

open access: yesThe Scientific World Journal, 2014
We study local generalized (α,β)-derivations on algebras generated by their idempotents and give some important applications of our results.
Ajda Fošner
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

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