Results 71 to 80 of about 94,277 (276)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

f-Fixed Points of Isotone f-Derivations on a Lattice

Discussiones Mathematicae - General Algebra and Applications, 2019
In a recent paper, Çeven and Öztürk have generalized the notion of derivation on a lattice to f-derivation, where f is a given function of that lattice into itself.
Zedam Lemnaouar, Yettou Mourad, Amroune Abdelaziz   +2 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

On Generalized Semiderivations of Prime Near Rings

International Journal of Mathematics and Mathematical Sciences, 2015
Let N be a near ring. An additive mapping F:N→N is said to be a generalized semiderivation on N if there exists a semiderivation d:N→N associated with a function g:N→N such that F(xy)=F(x)y+g(x)d(y)=d(x)g(y)+xF(y) and F(g(x))=g(F(x)) for all x,y∈N.
Abdelkarim Boua, A. Raji, Asma Ali, Farhat Ali   +3 more
doaj   +1 more source

Network Localization of Fatigue in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo, Jaakko Kungshamn, Albert Bellmunt‐Gil, Silvia Tommasin, Abhineet Ojha, Matias Viitala, Juho Aaltonen, Jyrki Lötjönen, Juha Koikkalainen, Pauli Ylikotila, Patrizia Pantano, Merja Soilu‐Hänninen, Juho Joutsa   +12 more
wiley   +1 more source

Generalized Hyers-Ulam Stability of Generalized (𝑁,𝐾)-Derivations

Abstract and Applied Analysis, 2009
Let 3≤𝑛, and 3≤𝑘≤𝑛 be positive integers. Let 𝐴 be an algebra and let 𝑋 be an 𝐴-bimodule. A ℂ-linear mapping 𝑑∶𝐴→𝑋 is called a generalized (𝑛,𝑘)-derivation if there exists a (𝑘−1)-derivation 𝛿∶𝐴→𝑋 such that 𝑑(𝑎1𝑎2⋯𝑎𝑛)=𝛿(𝑎1)𝑎2⋯𝑎𝑛+𝑎1𝛿(𝑎2)𝑎3⋯𝑎𝑛+⋯+𝑎1𝑎2⋯𝑎𝑘−2𝛿(
M. Eshaghi Gordji, J. M. Rassias, N. Ghobadipour   +2 more
doaj   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

On Weak Generalized Amenability of Triangular Banach Algebras

Journal of Mathematical Extension, 2014
Let A1, A2 be unital Banach algebras and X be an A1 − A2− module. Applying the concept of module maps, (inner) module generalized derivations and generalized first cohomology groups, we present several results concerning the relations between module ...
M. Mosadeq
doaj  

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source