Results 101 to 110 of about 261,441 (340)

SPG4 and Dementia: Expanding the Clinical Spectrum

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza   +19 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Infinite propagation speed and asymptotic behavior for a generalized Camassa-Holm equation

open access: yes上海师范大学学报. 自然科学版, 2018
This paper is devoted to the Cauchy problem for a generalized Camassa-Holm equation. First, we prove that the solution u(x, t) to the generalized Camassa-Holm equation with compactly supported initial data u0(x) instantly loses compact support.
Cui Wenjun, Han Lijia, Wang Duan
doaj   +1 more source

Correlation of sociodemographic profiles with psychological problems among hospitalized patients receiving unplanned hemodialysis

open access: yesRenal Failure, 2020
Purpose In this prospective study, we aimed to examine the sociodemographic factors and clinical factors associated with psychological disorders in chronic kidney disease (CKD) patients receiving unplanned hemodialysis (HD).
Yu-Yin Kao   +3 more
doaj   +1 more source

GMV control of nonlinear multivariable systems [PDF]

open access: yes, 2004
A Generalized Minimum Variance control law is derived for the control of nonlinear, possibly time-varying multivariable systems. The solution for the control law is original and was obtained in the time-domain using a simple operator representation of ...
Grimble, M.J.
core  

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak   +4 more
wiley   +1 more source

Non-singular terminal super-twitsing control of servo systems with backlash

open access: yesScientific Reports
To improve the control performance of servo systems under time-varying disturbances, a nonsingular terminal super twisting sliding mode control (NTSTC) method based on a reduced-order generalized proportional-integral observer is proposed.
Taoyu Wang, Shiyan Sun, Qijie Chen
doaj   +1 more source

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