Results 81 to 90 of about 6,245,235 (232)
Advanced Science, EarlyView.Through integrated proteomic and metabolomic profiling, Zhao et al. identified three molecular subtypes of high‐grade serous ovarian cancer. The high‐risk subtype exhibits activated arachidonic acid metabolism and cyclooxygenase‐2 overexpression. This metabolic axis promotes M2‐like macrophage infiltration, which contributes to platinum resistance ...
Yuxi Zhao +11 more
wiley +1 more source
Neuropsychiatric Disease and TreatmentShaoqi Mou,1,* Shiyu Yan,1,* Shanhong Shen,2 Yibin Shuai,2 Gang Li,3 Zhongxia Shen,2 Ping Shen2 1Department of Psychiatry, Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Sleep Medical Center, Huzhou Third ...
Mou S +6 more
doaj
Advanced Science, EarlyView.Using grilled lamb skewers as a model system, this work builds a multiscale coupling framework from oral processing to retronasal aroma perception, reveals dual‐kinetic release patterns and Electroencephalogram‐characterized central encoding features, and proposes an interpretable physics‐guided deep learning model validated by multiphysics simulation,
Che Shen +12 more
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Locally finite minimal non-FC-groups
, 1989 We recall that a group G is an FC-group if for every x∈G the set of conjugates {xg|g∈G} is a finite set. Our interest here is with those groups G which are not FC groups while every proper subgroup of G is an FC-group: such groups are called minimal non ...
PHILLIPS, RE +5 more
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Advanced Science, EarlyView.Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Atrial fibrillation (AF) increases the risk of stroke and heart failure, yet accurate quantification of AF burden in daily life remains difficult. Although smartwatch photoplethysmography (PPG) supports continuous monitoring, complex rhythms and signal noise can impair burden estimation.
Song Zuo +27 more
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UPPER TOPOLOGICAL GENERALIZED GROUPS [PDF]
, 2010 Here, we introduce the notion of generalized universal covers for topological generalized groups and present a method for constructing new topological generalized groups by using of universal covers.
Ghane, F.H., Hamed, Z.
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, 2019 (A) Bar diagrams show the effects of glycoprotein VI–fragment crystallizable (GPVI-Fc) (20 μg/ml; 133 nM), GPVI-Fc, and Fc cross-linked (XL) with anti–human-Fc immunoglobulin G (IgG) (GPVI-Fc*IgG-XL, Fc*IgG-XL; 133 nM) (left panels) or with anti–human-Fc
Kerstin Uhland (2092060) +14 more
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Advanced Science, EarlyView.Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim +6 more
wiley +1 more source
Advanced Science, EarlyView.Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon +27 more
wiley +1 more source