Results 91 to 100 of about 2,733 (260)

Identification of a Force‐Induced Sox9+Acan+ Transitional Subpopulation Linked to FGF2–FGFR2–ERK Signaling in Orthodontic Bone Remodeling

Advanced Science, EarlyView.
Mechanical loading induces a previously unrecognized Sox9+Acan+ transitional mesenchymal cell population in the periodontal ligament that promotes osteoclastogenesis via the FGF2–FGFR2–ERK axis. Targeting this mechanoresponsive stromal population using a localized GelMA@siRNA delivery strategy attenuates pathological osteoclast overactivation and root ...
Miao Tan, Minyu He, Mingrui Zong, Qiya Tang, Yinan Liu, Jiaju Deng, Shun Huang, Xiaoxiao Lei, Jie Li, Lan Huang   +9 more
wiley   +1 more source

Monolithic 3D Printing of Origami‐Inspired Soft Robotics from Sustainable Bio‐Based Resin

Advanced Science, EarlyView.
This work develops a photocurable, bio‐based resin from soybean oil for the monolithic fabrication of sustainable soft robots via Digital Light Processing. An origami‐inspired, vacuum‐actuated soft gripper is designed and fabricated, enabling reliable operation despite the material's lower elongation.
Ramin Montazeri, Hugo de Souza Oliveira, Xin Li, Qingchuan Song, Bastian E. Rapp, Dorothea Helmer, Edoardo Milana   +6 more
wiley   +1 more source

An Implantable Scaffold Sequentially Releasing STING Agonist and B7‐H3 Antibody for Bone Metastasis Immunotherapy

Advanced Science, EarlyView.
We developed an implantable dual‐drug depot using GelMA for bone metastasis treatment, co‐delivering MSA‐2 and αB7‐H3‐loaded CaCO3 microparticles. Sustained release from GelMA scaffold enables MSA‐2 to activate STING signaling and enhance T‐cell infiltration and activation, while sequentially released αB7‐H3 blocks MSA‐2‐induced B7‐H3 upregulation ...
Qijun Lin, Hong Xiao, Shuai Fan, Kaimin Cai, Yanteng Xu, Xinwen Wang, Guanhong Chen, Chuandong Lang, Xinsheng Peng, Mingqiang Li, Yuhu Dai   +10 more
wiley   +1 more source

Generalized J-integral – mathematical foundation

Boundary Value Problems
This article describes the mathematics for building the foundations of the theory of the Generalized J-integral (GJ-integral) in various variational problems defined on D that gives the shape derivative on singular points such as boundaries, cracks ...
Kohji Ohtsuka
doaj   +1 more source

Structural and Mechanical Dynamics of Polymer Membranes Across Multilength Scales

Advanced Science, EarlyView.
Distinct surface‐to‐bulk mechanical contrasts in polymer membranes were unveiled, highlighting the need to probe both regions to fully capture their functional behavior. By integrating in situ SAXS–WAXS with AFM‐based nanomechanics, nanodomain‐level heterogeneity and real‐time structural transformations induced by thermal and mechanical stimuli were ...
Rifan Hardian, Hakkim Vovusha, Yue Yuan, Changxia Shi, Eugene Y.‐X. Chen, Mario Lanza, Gyorgy Szekely   +6 more
wiley   +1 more source

Polyrotaxane‐Assembled Semi‐Interpenetrating Polymer Electrolytes Enabling High‐Voltage Lithium Metal Batteries

Advanced Science, EarlyView.
This work develops a polyrotaxane‐based supramolecular semi‐interpenetrating network electrolyte. Its unique architecture decouples ion transport, achieving high ionic conductivity (0.18 mS cm−1), a superior Li+ transference number (> 0.73), and an extended electrochemical window (> 4.9 V), thereby significantly enhancing the performance of high ...
Tianyi Wang, Yue Ma, Jiacheng Liu, Zhaofan He, Jin Liang, Kailiang Ren, Jie Kong   +6 more
wiley   +1 more source

Lattice Genome Framework for Regionally Tailored Component‐Level Multi‐Objective Design in Additive Manufacturing

Advanced Science, EarlyView.
A Lattice Genome framework links geometric and process “genes” to lattice “phenotypes” via correction‐calibrated high‐throughput simulations and a growing performance database. Genome‐driven retrieval and recombination of unit cells enables component‐level, regionally tailored multi‐objective design: stress fields are programmed under constant relative
Haoyuan Deng, Yufan Zhao, Mingyang Cao, Haiou Yang, Pan Wang, Hongze Wang, Hao Wang, Akihiko Chiba, Xin Lin   +8 more
wiley   +1 more source

Deformation‐Induced Formation of Stray Grains in Additive Manufacturing of Single Crystals

Advanced Science, EarlyView.
Stray grain formation severely limits the additive manufacturing of single‐crystal alloys. By integrating in situ synchrotron techniques, ex situ characterization, and multi‐scale multi‐physics modeling, the authors reveal that stray grains originate from dislocations at the solid‐liquid interface, rather than thermal supercooling in conventional ...
Dongsheng Zhang, Zixu Guo, Yuxiao Li, Lu Wang, Yu Wu, Darui Sun, Wentao Yan, Yuanyuan Guo, Han Wang, Wei Liu, Ye Tao, Bingbing Zhang   +11 more
wiley   +1 more source

Data‐Driven Design and Fabrication of Heat‐Resistant, Ultrastrong, Lightweight Aluminum‐Based Entropy Alloy by Additive Manufacturing

Advanced Science, EarlyView.
A data‐driven strategy integrating quantum machine learning (QML) and high‐throughput computing overcomes hot‐cracking limitation to design a novel lightweight aluminum‐based entropy alloy for additive manufacturing. The fabrication transforms brittle intermetallics into deformable hierarchical nanostructures, yielding ultrastrong strength (>1 GPa) and
Enmao Wang, Chao Ding, Danyang Zhou, Chenjin Xu, Swee Leong Sing, Jianzhong Jiang, Huibin Wu   +6 more
wiley   +1 more source

A Si‐MoSe2 Heterostructured Anode with Enhanced Thermal Transport and Electrochemical Performance for Liquid and All‐Solid‐State Lithium‐Ion Batteries

Advanced Science, EarlyView.
Chemically bonded Si@MoSe2@C heterointerfaces with robust Si─Se─Mo bonds enable high‐performance Si anodes. Lattice‐matched MoSe2 on porous Si with carbon‐protective coating delivers 1054 mAh g−1 after 100 cycles and 99.5% Coulombic efficiency over 400 cycles.
Yajun Zhu, Jiaqi Gu, Guangwu Zhang, Tianli Han, Yang Lu, Zhongbing Li, Hang Su, Fei Wang, Haojun Xu, Wentuan Bi, Qiye Zheng, Jinyun Liu   +11 more
wiley   +1 more source