Results 121 to 130 of about 1,474,584 (283)

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Negative Binomial Two-Parameter Lindley generalized linear model for modeling count data

open access: yesResearch in Statistics
Zero-inflated data, characterized by excessive zero counts, is a common challenge in various fields, particularly in insurance data. In most cases, count data exhibits overdispersion and excess zeros; models that fail to account for these characteristics
Samwel Karanja Kamau   +3 more
doaj   +1 more source

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

The Negative Binomial Distribution Efficiency in Finite Mixture of Semi-parametric Generalized Linear Models

open access: yesپژوهش‌های ریاضی, 2019
Introduction Selection the appropriate statistical model for the response variable is one of the most important problem in the finite mixture of generalized linear models.
Farzad Eskandari
doaj  

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

Drought forecasting with regionalization of climate variables and generalized linear model

open access: yesMeteorological Applications
Spring drought forecasting is essential in South Korea for managing water resources reliably and cultivating agricultural products efficiently, as seasonal rainfall difference often drives water shortage during spring.
Taesam Lee   +3 more
doaj   +1 more source

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