Results 101 to 110 of about 332,658 (263)

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Normal-Power-Logistic Distribution: Properties and Application in Generalized Linear Model. [PDF]

J Indian Soc Probab Stat, 2023
Ekum MI, Adamu MO, Akarawak EEE.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Semiparametric analysis of a generalized linear model with multiple covariates subject to detection limits. [PDF]

Stat Med, 2022
Chen LW, Fine JP, Bair E, Ritter VS, McElrath TF, Cantonwine DE, Meeker JD, Ferguson KK, Zhao S.   +8 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Drought forecasting with regionalization of climate variables and generalized linear model

Meteorological Applications
Spring drought forecasting is essential in South Korea for managing water resources reliably and cultivating agricultural products efficiently, as seasonal rainfall difference often drives water shortage during spring.
Taesam Lee, Yejin Kong, Joo‐Heon Lee, Chang‐Hee Won   +3 more
doaj   +1 more source

Effect of a school-linked life skills intervention on adolescents' sexual and reproductive health skills in Guji zone, Ethiopia (CRT)-A generalized linear model. [PDF]

Front Public Health, 2023
Godana G, Garoma S, Ayers N, Abera M.
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Retracted: Serum Levels of Mitochondrial Fission- and Fusion-Related Genes of Coal Workers' Pneumoconiosis and Risk Factor Analysis Based on a Generalized Linear Model. [PDF]

Appl Bionics Biomech, 2023
And Biomechanics AB.
europepmc   +1 more source

Generalized linear models

, 2015
AbstractGeneralized Linear Modeling (GLM) unifies several statistical techniques, providing a stable and modular foundation on which to build a useful working knowledge of statistical modeling. GLMs enable a re-interpretation of previously learned ANOVA and regression techniques and integrate well with more advanced modeling techniques introduced in ...
openaire   +5 more sources