Results 91 to 100 of about 332,658 (263)
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Outbreak detection algorithms based on generalized linear model: a review with new practical examples. [PDF]
BMC Med Res Methodol, 2023 Zareie B +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Evaluation of oriental beech (Fagus orientalis L.) site productivity using generalized additive model (Case study: Tarbiat Modares University Forest Research Station) [PDF]
مجله جنگل ایران, 2015 Site productivity is a key indicator of forest ecosystem; therefore it is an important criterion for forest manager for estimating the yield, annual exploitation and growth, and choosing the most suitable tree species for sites as well.
doaj
Negative Binomial Two-Parameter Lindley generalized linear model for modeling count data
Research in StatisticsZero-inflated data, characterized by excessive zero counts, is a common challenge in various fields, particularly in insurance data. In most cases, count data exhibits overdispersion and excess zeros; models that fail to account for these characteristics
Samwel Karanja Kamau +3 more
doaj +1 more source
Evaluation of frequentist test statistics using constrained statistical inference in the context of the generalized linear model. [PDF]
Health Psychol Behav Med, 2023 Keck C, Mayer A, Rosseel Y.
europepmc +1 more source