Results 81 to 90 of about 332,658 (263)
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Exploring Global Temperature Oscillations Using a Generalized Linear Box Model
Solutions including oscillatory responses to monotonic forcing are derived for a generalized energy balance box model, and used to help explore general circulation model (GCM) global surface temperature responses to CO2 forcing.
Hege‐Beate Fredriksen +2 more
doaj +1 more source
L_2 Differentiability of Generalized Linear Models
10 ...
Pupashenko, Daria +2 more
openaire +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Estimation of the Contaminant Risk Level of Petroleum Residues Applying FDA Techniques
In the process of oil extraction, specifically in therefinement and industrialization of hydrocarbons, as is known,multiple wastes are highly polluting for the soil, water and air.In this work, the risk level of these wastes in affected areasis estimated
Miguel Flores +3 more
doaj
Leaf count overdispersion in coffee seedlings
: Coffee crops play an important role in Brazilian agriculture, with a high level of social and economic participation resulting from the jobs created in the supply chain and from the income obtained by producers and the revenue generated for the ...
Edilson Marcelino Silva +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source

