Results 61 to 70 of about 373,771 (313)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Quantum Generalized Linear Models

CoRR, 2019
Generalized linear models (GLM) are link function based statistical models. Many supervised learning algorithms are extensions of GLMs and have link functions built into the algorithm to model different outcome distributions. There are two major drawbacks when using this approach in applications using real world datasets.
Colleen M. Farrelly, Srikanth Namuduri, Uchenna Chukwu   +2 more
openaire   +2 more sources

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

FedGMMAT: Federated generalized linear mixed model association tests.

PLoS Computational Biology
Increasing genetic and phenotypic data size is critical for understanding the genetic determinants of diseases. Evidently, establishing practical means for collaboration and data sharing among institutions is a fundamental methodological barrier for ...
Wentao Li, Han Chen, Xiaoqian Jiang, Arif Harmanci   +3 more
doaj   +1 more source

Oil Production-Energy Consumption Relationship Modeling Using Generalized Linear Model

Energies
This study investigates the relationship between energy consumption and oil production in petroleum extraction using a Generalized Linear Model (GLM).
Qian Wei, Chao Chi, Wei Wang, Jun Mao, Dengyun Ma, Kailai Hu, Junru Luo   +6 more
doaj   +1 more source

Space–time proper generalized decompositions for the resolution of transient elastodynamic models [PDF]

, 2013
In this paper, we investigate ability of proper generalized decomposition (PGD) to solve transient elastodynamic models in space–time domain. Classical methods use time integration schemes and an incremental resolution process.
BOUCINHA, Lucas, AMMAR, Amine, GRAVOUIL, Anthony   +2 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Albatross analytics a hands-on into practice: statistical and data science application

Journal of Big Data, 2022
Albatross Analytics is a statistical and data science data processing platform that researchers can use in disciplines of various fields. Albatross Analytics makes it easy to implement fundamental analysis for various regressions with random model ...
Rezzy Eko Caraka, Youngjo Lee, Jeongseop Han, Hangbin Lee, Maengseok Noh, Il Do Ha, Prana Ugiana Gio, Bens Pardamean   +7 more
doaj   +1 more source