Revealing Airflow–Particle Dynamics in Dry Powder Inhalers
An integrated framework combining device and formulation characterization, CFD–DEM simulations, and interpretable machine learning is established. This framework reveals how airflow and particle interactions govern powder dispersion across prevailing dry powder inhalers.
Jiale Chen +12 more
wiley +1 more source
Reliability Assessment of MEMS Gyroscopes via Dual-Mechanism Synergistic Degradation: A Generalized Linear Model with Physics-Informed Wiener Processes. [PDF]
Yang P, Liu Z, Liang Y, Guo X, Geng H.
europepmc +1 more source
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin +10 more
wiley +1 more source
Improving sampling efficacy on high-dimensional distributions with thin high-density regions using Conservative Hamiltonian Monte Carlo. [PDF]
McGregor G, Wan ATS.
europepmc +1 more source
A Novel Approach to Energy Management in Electric Steelworks
Feed‐forward neural networks are exploited to estimate electric energy consumptions of the electric arc furnace and ladle furnace processes. The models are used to optimize production schedule so that more energy intensive grades are produced when the cost of energy is lower.
Valentina Colla +12 more
wiley +1 more source
Assessing a reduced-channel algorithm for end-to-end seizure detection on multiday EEG using inter-rater agreement with epileptologists. [PDF]
Tosi Z +5 more
europepmc +1 more source
Abstract Writing is crucial in tertiary education, yet enhancing the complexity of academic writing presents significant challenges for second language (L2) learners. This study explores the potential of dialogue journal writing (DJW), an interactive and low‐stress classroom activity, to enhance writing complexity among novice L2 writers.
Barry Lee Reynolds +2 more
wiley +1 more source
A variant of Newton's method for generalized equations
Summary: In this article, we study a variant of Newton's method of the following form \[ 0\in f(x_k)+ h\nabla f(x_k) (x_{k+1}-x_k)+ F(x_{k+1}), \] where \(f\) is a function whose Fréchet derivative is \(K\)-Lipschitz, \(F\) is a set-valued map between two Banach spaces \(X\) and \(Y\) and \(h\) is a constant.
Célia, Jean-Alexis, Alain, Pietrus
openaire +3 more sources
Stochastic gradient descent estimation of generalized matrix factorization models with application to single-cell RNA sequencing data. [PDF]
Castiglione C +3 more
europepmc +1 more source
Abstract Repeated viewing is reportedly a common learning and pedagogical strategy among autonomous second language (L2) learners and language teachers. This experimental study examined the extent to which sequential captioning use facilitates the acquisition of multiword expressions (MWEs) through repeated viewing under incidental learning conditions.
Kenneth W. Y. Li, Yaxin Ni
wiley +1 more source

