Results 191 to 200 of about 1,609,080 (232)

Examining the evolving roles of quantity surveyors in achieving the United Nations sustainable development goals. [PDF]

PLoS One
Gasu JS, Eluerkeh K, Sackey KNYS, Nani G, Dompey AMA, Simpeh E, Agyekum K.   +6 more
europepmc   +1 more source

Noninvasive Detection and Subtyping of Esophageal Cancer by Circulating Cell‐Free mtDNA Fragmentomics: A Multi‐Center Validation Study

Advanced Science, EarlyView.
Circulating cell‐free mitochondrial DNA provides a robust, noninvasive platform for early detection and histological subtyping of esophageal cancer. This large multi‐center study validates consistently high accuracy across ethnically and geographically diverse cohorts, demonstrating strong potential to transform clinical management. ABSTRACT Esophageal
Yue Liu, Wenying Yang, Yu Li, Siyuan Wang, Xiang Li, Fan Peng, Miao Dang, Huanqin Zhang, Huanmin Jiao, Yuqing Yang, Zhaoquan Su, Xiumin Ma, Zhiyun Gong, Renquan Lu, Jinliang Xing, Yang Liu   +15 more
wiley   +1 more source

Tobacco and alcohol use following first vs. consecutive cardiovascular events: a prospective longitudinal study. [PDF]

Front Cardiovasc Med
Pons-Cabrera MT, Szałata K, Caballeria E, Navarro-Cortés L, Oliveras C, Bueno L, Roqué M, Falces C, Borràs R, Pintor L, Balcells M, López-Pelayo H.   +11 more
europepmc   +1 more source

Enriched Soil Organic Carbon Underpins Long‐Term Stable Crop Productivity Across China's Croplands

Advanced Science, EarlyView.
Quantifying the nonlinear relationships and causal effects of soil organic carbon (SOC) on crop stability reveals specific critical thresholds and saturation points. This partitions the national SOC spectrum into three functional phases. Integrating these spatial delineations with high‐resolution maps of marginal gains pinpoints regions with the ...
Yuyang Huang, Yulin Shangguan, Zhongkui Luo, Peng Zhu, David Makowski, Zhenzhong Zeng, Qingxu Ma, Min Wei, Yuanyuan Du, Su Ye, Zhou Shi, Songchao Chen   +11 more
wiley   +1 more source

The microbiota-lymphocyte protective axis (MLPA): a novel paradigm for overcoming radiation-induced lymphopenia (RIL) and potentiating the efficacy of tumor immuno-combination therapy. [PDF]

Cancer Immunol Immunother
Chen Y, Chen S, Zhang H, Song B, Xu Y.
europepmc   +1 more source

Advances in Josephson Junction Materials and Processes Toward Practical Quantum Computing

Advanced Science, EarlyView.
Emerging materials for quantum computing, including crystalline materials, two‐dimensional van der Waals materials, two‐dimensional electron gas systems, ferromagnets, and unconventional (e.g., d‐wave) superconductors, offer opportunities to engineer next‐generation Josephson junctions.
Hyunseong Kim, Gyunghyun Jang, Seungwon Jin, Jaewon An, Dongbin Shin, Hyeon‐Jin Shin, Jie Luo, Akel Hashim, Irfan Siddiqi, Yosep Kim, Long B. Nguyen, Hoon Hahn Yoon   +11 more
wiley   +1 more source

Aging-Related Changes in the Injury Response of the Peripheral Nervous System. [PDF]

Neurosci Bull
Cen YY, Wang MY, Song QX, Gao XL, Zhou C, Li CJ, Liu F, Zhang YY, Shen JF.   +8 more
europepmc   +1 more source

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

NDFIP2 Suppresses Colorectal Cancer Metastasis Through DDX3X‐Dependent R‐Loop Remodeling and GNG13 Transcriptional Activation

Advanced Science, EarlyView.
NDFIP2 recruits NEDD4 to promote K48‐linked ubiquitination and proteasomal degradation of DDX3X, leading to R‐loop accumulation and CTCF‐dependent suppression of GNG13 transcription. Consequently, PI3K/AKT signaling, EMT, stemness, and colorectal cancer metastasis are inhibited.
Enjian Zhang, Yanfang Li, Jiaxin Shu, Shang Xu, Heng Lv, Chong Zhang, Pengbo Zhang, Nai Wu, Shuai Gong, Xiuzhong Zhang, Zeqiang Ren, Yi Zhang, Xin Liu   +12 more
wiley   +1 more source

Leveraging Data Science for Conducting Observational Studies: Highlighting Advantages and Limitations Throughout the Evaluation of a Use Case. [PDF]

Mayo Clin Proc Digit Health
Rios-Duarte JA, Pick TL, Robson TN, Lin RJ, Todd A, Romero-Brufau S, Vidal NY.   +6 more
europepmc   +1 more source