Results 81 to 90 of about 5,814 (191)

Real‐World Safety Profile of Spesolimab in Generalized Pustular Psoriasis: Insights From Japan as Part of a Multinational Expanded Access Program (EAP)

The Journal of Dermatology, Volume 53, Issue 2, Page 351-356, February 2026.
ABSTRACT Generalized pustular psoriasis (GPP) is a heterogeneous, systemic neutrophilic inflammatory disease, characterized by chronic symptoms and recurrent flares, which can be potentially life‐threatening. Spesolimab, an interleukin‐36 receptor antagonist, has been approved to treat GPP flares in many countries including Japan.
Akimichi Morita, Yayoi Tada, Yuichiro Tsunemi, Mayumi Komine, Takuro Kanekura, Shinichi Imafuku, Toshiya Takahashi, Xuemei Ding, Nichiren Pillai, Morihisa Saitoh, Rafael Sani Simoes, Nora Pöntynen, Keiichi Yamanaka   +12 more
wiley   +1 more source

Six‐Year Trends in Real‐World Data Use for Post‐Marketing Surveillance of New Medical Products in Japan

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT The Ministerial Ordinance on Good Post‐Marketing Study Practice for Drugs was amended by the Ministry of Health, Labour and Welfare (MHLW) in 2018 to clearly define post‐marketing database studies (DBS) as a measure of pharmacovigilance activities for approved medical products in Japan.
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Diagnosis and screening of patients with generalized pustular psoriasis

Psoriasis: Targets and Therapy, 2019
Karen Ly,* Kristen M Beck*, Mary P Smith, Quinn Thibodeaux, Tina BhutaniDepartment of Dermatology, University of California, San Francisco, CA, USA*These authors contributed equally to this work Abstract: Generalized pustular psoriasis (GPP) is a rare ...
Ly K, Beck KM, Smith MP, Thibodeaux Q, Bhutani T   +4 more
doaj  

Shame‐related disorders in patients with atopic dermatitis and psoriasis – An exploratory, cross‐sectional interview study on the prevalence and correlates of body dysmorphic disorder and social anxiety disorder

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 2, Page 196-204, February 2026.
Summary Background and objectives Atopic dermatitis (AD) and psoriasis (Pso) are frequently associated with psychological distress. This study evaluated the prevalence and correlates of shame‐related disorders (SRD), namely body dysmorphic disorder (BDD) and social anxiety disorder (SAD), in patients with AD and Pso. Patients and methods A monocentric,
Clara Wülfing, Carsten Spitzer, Laura Lübke, Steffen Emmert, Alexander Thiem   +4 more
wiley   +1 more source

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ [PDF]

, 2017
The pro-inflammatory cytokine IL-36γ is highly expressed in epithelial cells and is a pivotal mediator of epithelial inflammation. In particular, IL-36γ is strongly associated with the inflammatory skin disease psoriasis. As with other IL-1 cytokines, IL-
Ade Alase, Boutet, Brix, Buchan, Dennis McGonagle, Dinarello, Enk, Henry, Jens M. Baron, Joseph S. Ainscough, Macleod, Mahil, Martin, Martin Stacey, Miriam Wittmann, Ozdemir, Papini, Rosella Brakefield, Rubartelli, Schönefuss, Tom Macleod   +20 more
core   +1 more source

Dual impact of smoking cessation and post‐cessation weight change on psoriasis

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 2, Page 285-295, February 2026.
Although smoking cessation generally reduced the risk of psoriasis, especially psoriasis vulgaris and palmoplantar pustulosis, post‐cessation weight gain weakened this benefit, mainly for psoriasis vulgaris. Nonetheless, cessation maintained a substantial protective effect against palmoplantar pustulosis, and long‐term advantages outweighed the adverse
Seong Rae Kim, Young‐Geun Choi, Seong Jin Jo   +2 more
wiley   +1 more source

"ACUTE GENERALIZED PUSTULAR PSORIASIS AND IDIOPATHIC HYPOPARATHYROIDISM IN AN ADOLESCENT GIRL" [PDF]

Acta Medica Iranica, 2004
Generalized pustular psoriasis with hypoparathyroidism has been reported previously often as a post thyroidectomy syndrome with hypoalbuminemia and hypocalcemia. But reports on association of pustular psoriasis with idiopathic hypoparathyroidism are very
Sh.S.Ashkevari A.Maboodi
doaj   +1 more source

A Pediatric Case of Acute Generalized Pustular Eruption without Streptococcal Infection

Case Reports in Dermatology, 2016
Generalized pustular lesions characterized by acute onset with fever occur in pustulosis acuta generalisata, acute generalized exanthematous pustulosis, and generalized pustular psoriasis.
Nobuko Tabata, Hideka Yoshizawa
doaj   +1 more source

2015 Annual Meeting of the Medical Dermatology Society [PDF]

, 1871
Von J ...
Jettinger, J.
core   +1 more source

Acute generalized exanthematous pustulosis in a patient with plaque psoriasis

Saudi Journal of Medicine and Medical Sciences, 2014
Acute generalized exanthematous pustulosis (AGEP) is an acute febrile drug eruption characterized by sudden occurrence of numerous, non-follicular, pinhead-sized pustules. This usually occurs 3-5 days after the commencement of treatment.
Khalid A Al Hawsawi, Hawazin D Jan, Ali A Al Raddadi, Aymen H Alharbi, Mazin M Al Jabri, Mohammed B Satti   +5 more
doaj   +1 more source