Results 91 to 100 of about 4,306,668 (246)

Generalized splines in ℝn and optimal control [PDF]

open access: yes, 2006
We give a new time-dependent definition of spline curves in ℝn, which extends a recent definition of vector-valued splines introduced by Rodrigues and Silva Leite for the time-independent case.
Rodrigues, R.C., Torres, D.F.M.
core   +1 more source

Synthesis of uniformly distributed optimal control with nonlinear optimization of oscillatory processes

open access: yesҚарағанды университетінің хабаршысы. Математика сериясы
In the article the problem of synthesizing uniformly distributed optimal control for nonlinear optimization of oscillatory processes described by integro-differential partial differential equations with the Volterra integral operator was explored.
A. Kerimbekov   +2 more
doaj   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

A generalized FKKM theorem and variational inequality [PDF]

open access: yes
We present a generalized FKKM Theorem and it's application to the existence of solution for the variationals inequalities using a generalized coercivity type condition for correspondences defined in L-space.L-structure, L-spaces, L-KKM correspondences, L-
Hakim Hammami
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Generalized solutions to the gKdV equation

open access: yesElectronic Journal of Differential Equations, 2010
In this article we study the Cauchy problem in $mathcal{G}_2((0,T)imes mathbb{R})$ (the algebra of generalized functions, in the sense of Colombeau) for the generalized Korteweg-de Vries equation, with initial condition $varphi in mathcal{G}_2(mathbb{
Maurilio Marcio Melo
doaj  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source

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