Results 61 to 70 of about 121,548 (267)

MULTITEMPORAL GENERALIZATION OF THE SCHWARZSCHILD SOLUTION [PDF]

open access: yesInternational Journal of Modern Physics D, 1995
The n-time generalization of the Schwarzschild solution is considered. The equations of geodesics for the metric are integrated. The multitemporal analogues of Newton’s laws for the extended objects described by the solution are suggested. The scalar-vacuum generalization of the solution is also presented.
Ivashchuk, Vladimir D.   +1 more
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Generating Solutions via Sigma-Models [PDF]

open access: yesProgress of Theoretical Physics Supplement, 2008
An updated version of the talk given at ICGA8 and published in the Proceedings.
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Singular solutions to Protter's problem for the 3-D wave equation involving lower order terms

open access: yesElectronic Journal of Differential Equations, 2003
In 1952, at a conference in New York, Protter formulated some boundary value problems for the wave equation, which are three-dimensional analogues of the Darboux problems (or Cauchy-Goursat problems) on the plane.
Myron K. Grammatikopoulos   +2 more
doaj  

Generalized Reflexive and Generalized Antireflexive Solutions to a System of Matrix Equations

open access: yesJournal of Applied Mathematics, 2014
Two efficient iterative algorithms are presented to solve a system of matrix equations A1X1B1 + A2X2B2=E, C1X1D1 + C2X2D2=F over generalized reflexive and generalized antireflexive matrices.
Yong Lin, Qing-Wen Wang
doaj   +1 more source

Solution of Generic Nonlinear Oscillators

open access: yesApplied Mathematics and Computation, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Adomian, G., Meyers, R.E., Rach, R.
openaire   +2 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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