Results 21 to 30 of about 2,003,104 (241)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Kernel regression based machine translation [PDF]
, 2007 We present a novel machine translation framework based on kernel regression techniques. In our model, the translation task is viewed as a string-to-string mapping, for which a regression type learning is employed with both the source and the target ...
Zhuoran Wang +8 more
core +1 more source
Integrable operators and squares of Hankel operators. [PDF]
, 2008 Integrable operators arise in random matrix teory, where they describe the asymptotic distributions of large self-adjoint random matrices from the generalized unitary ensembles.
Blower, Gordon
core +5 more sources
Metric-Induced Rotations with Gielis-Based Geometry
MathematicsIn this work, we present a generalized geometric framework that extends quaternion-based rotation and translation operators within a generalized inner product and vector product setting defined on Gielis-type superquadrics.
Zehra Özdemir, Johan Gielis
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Lieb-Schultz-Mattis anomalies as obstructions to gauging (non-on-site) symmetries
SciPost PhysicsWe study 't Hooft anomalies of global symmetries in 1+1d lattice Hamiltonian systems. We consider anomalies in internal and lattice translation symmetries.
Sahand Seifnashri
doaj +1 more source
Generalized integral transforms with the translation operator on function space
Filomat, 2019 Main goal of this paper is to establish various basic formulas for the generalized integral transform involving the generalized convolution product. In order to establish these formulas, we use the translation operator which was introduced in [9].
Chang, Seung Jun +2 more
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Discrete Tracy--Widom operators. [PDF]
, 2009 Integrable operators arise in random matrix theory, where they describe the asymptotic eigenvalue distribution of large self-adjoint random matrices from the generalized unitary ensembles.
McCafferty, Andrew, Blower, Gordon
core +4 more sources