Results 61 to 70 of about 1,694,886 (274)

Media Use and Political Engagement: Cross-Cultural Approaches| Media Use and Green Lifestyle Politics in Diverse Cultural Contexts of Postmaterialist Orientation and Generalized Trust: Findings From a Multilevel Analysis

International Journal of Communication, 2023
In lifestyle politics, citizens take political action by adapting their everyday lives to address transnational challenges, such as climate change. An important driver of lifestyle politics is exposure to media—both mass media, serving as important ...
Laura Leissner
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Trusting strangers – The concept of generalized trust in perspective

, 2002
Generalisiertes Vertrauen ist eine wichtige gesellschaftliche Ressource und ist als integraler Aspekt und Messinstrument des sozialen Kapitals anerkannt. Dieser Artikel gibt einen Überblick über das Konzept des generalisierten Vertrauens. Hierzu wird zunächst generalisiertes Vertrauen mit anderen Formen von Vertrauen in der interdisziplinären Literatur
openaire   +2 more sources

Generative AI, Innovation, and Trust

The Journal of Applied Behavioral Science
Our paper explores the integration of generative artificial intelligence (GenAI) into organizations’ innovation and new product development processes, focusing on when and how to trust AI-generated outcomes in this context. We propose a framework to assess the level of trust required based on task-specific needs and the distinction between general and ...
Piller, Frank Thomas, Srour, Mahdi, Marion, Tucker J.   +2 more
openaire   +2 more sources

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

2010 Annual Report

Oregon Wave Energy Trust (OWET) is a nonprofit public-private partnership funded by the Oregon Innovation Council. Its mission is to support the responsible development of wave energy in Oregon. OWET emphasizes an inclusive, collaborative model to ensure
Oregon Wave Energy Trust
core   +6 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The Social Software of Corporate Governance: A Systems Analysis of Generalized Trust and Cultural Ecosystems

Systems
Corporate governance is a complex, adaptive open system; yet it is usually modeled, in the classical agency tradition, as a closed matrix of legal and financial contracts. Adopting an open systems perspective, we decode the “social software”—the informal
Vincent O’Connell, Fabian Jintae Froese   +1 more
doaj   +1 more source