Results 81 to 90 of about 1,694,886 (274)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Does Diversity Drive Down Trust? [PDF]
Some researchers claim that diverse populations lead to less trust. Generalized trust is a core value that leads to positive outcomes in societies--from greater tolerance of minority groups and immigrants and willingness to do good deeds, to less ...
Eric M. Uslaner
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Aging and Cancer, EarlyView.This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
And mistrust take the hindmost: generalized trust in Denmark from 1990-2008
Nordic Journal of Social Research, 2014 While most countries are experiencing stable or declining rates of generalized trust, this has not been the case in the Nordic countries, where levels of generalized trust have continued to increase.
Morten Frederiksen
doaj +1 more source
Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen +11 more
wiley +1 more source
Trust and Trustworthiness in the Fourth and Fifth Estates [PDF]
, 2009 The high contemporary salience in the social sciences of the topics of "trust" and "trustworthiness" has focused attention on the mass media’s putative role in eroding trust.
Collins, Richard, Collins, R.
core +3 more sources
Learning to trust strangers: an evolutionary perspective [PDF]
What if living in a relatively trustworthy society was sufficient to blindly trust strangers? In this paper we interpret generalized trust as a learning process and analyse the trust game paradox in light of the replicator dynamics.
Tarik Tazdaït, Pierre Courtois
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RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Historical Roots of Generalized Trust in Polish Society
International Journal of Management and Economics, 2014 The article analyses how historical events shape generalized trust in contemporary Polish society. The analysis consists of a set of logistic regression models.
Borowiecki Łukasz
doaj +1 more source
The authors explore the relationship between transaction costs and generalized trust. Using panel data from 2,100 households in 135 rural communities of the Philippines, the paper shows that where transaction costs are reduced (proxied by road ...
Chase, Robert S., Labonne, Julien
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