Results 81 to 90 of about 70,525 (245)

The role of generalized trust in COVID-19 vaccine acceptance. [PDF]

PLoS One, 2022
Eisnecker PS, Kroh M, Kühne S.
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

The Strength of Family Ties and Community Social Capital: A Mixed-Methods Examination of Zadar, Croatia

Comparative Southeast European Studies
Research has amply documented how the strong orientation toward the well-being of one’s own family can negatively affect an individual’s concern for issues within their broader community and the formation of civic social capital.
Dević Mislav
doaj   +1 more source

Iranian women's attitude toward childbearing and its' association with generalized trust, social support, marital satisfaction and governmental childbearing incentives. [PDF]

Heliyon, 2023
Alijanzadeh M, Bahrami N, Jafari E, Noori M, Miri F, Joftyar M, Griffiths MD, Alimoradi Z.   +7 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Generalizing Trust: How Outgroup-Trust Grows Beyond Ingroup-Trust

SSRN Electronic Journal, 2012
Trust in other people is general when it includes remote and dissimilar others (i.e., out-groups). But whether trust in outgroups can be created independently of trust in in-groups is controversial, and conclusive evidence has been unavailable so far.
Delhey, Jan, Welzel, Christian
openaire   +2 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

How emergency events change the lives of Russians: new challenges and the stability of adaptation

Социологическая наука и социальная практика
Based on the data from the Russian Longitudinal Monitoring Survey (RLMS-HSE), the peculiarities of Russians’ adaptation to the new social reality shaped by emergency events are analyzed. The main attention is paid to the dynamic analysis of the level and
Polina M. Kozyreva, Alexander I. Smirnov   +1 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Association between COVID-19 vaccine hesitancy and generalized trust, depression, generalized anxiety, and fear of COVID-19. [PDF]

BMC Public Health, 2022
Sekizawa Y, Hashimoto S, Denda K, Ochi S, So M.   +4 more
europepmc   +1 more source